Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4300726 | 1.00 | CARM1 (0.44) | CARM1PRMT6PRMT1PRMT8ACHE | |
| SCHEMBL24322555 | 1.00 | CARM1 (0.44) | CARM1PRMT6PRMT1PRMT8ACHE | |
| SCHEMBL24322374 | 0.95 | ACHE (0.43) | CARM1PRMT6PRMT1PRMT8ACHE | |
| SCHEMBL24322571 | 0.95 | ACHE (0.43) | CARM1PRMT6PRMT1PRMT8ACHE | |
| SCHEMBL11300211 | 0.84 | CXCR4 (0.44) | HRH3CXCR4SIGMAR1CYP1A2 | |
| SCHEMBL14603125 | 0.83 | ACHE (0.50) | CARM1PRMT6PRMT1PRMT8ACHE | |
| SCHEMBL4383201 | 0.81 | CXCR4 (0.36) | HRH3CXCR4 | |
| SCHEMBL4383519 | 0.79 | CXCR4 (0.35) | CXCR4 | |
| SCHEMBL4667716 | 0.79 | CXCR4 (0.35) | CXCR4 | |
| SCHEMBL8333360 | 0.79 | CYP1A2 (0.46) | HRH3POLBCXCR4SIGMAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
| US-20090270455-A1 | Therapeutic agent for intestinal diseases and visceral pain | AJINOMOTO CO., INC. (JP) | 2009-10-29 | — | — | US | disclosed |
| US-20050148632-A1 | Therapeutic agent for intestinal diseases and visceral pain | AJINOMOTO CO., INC. (JP) | 2005-07-07 | — | — | US | disclosed |
| EP-1541172-A1 | REMEDY FOR INTESTINAL DISEASES AND VISCERAL PAIN | Ajinomoto Co., Inc. (JP) | 2005-06-15 | — | — | EP | disclosed |
| EP-0912512-B1 | SULPHONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 2003-04-02 | — | — | EP | disclosed |
| US-6265408-B1 | PSYCHOLOGICAL DISORDERS; ANTIDEPRESSANT | SMITHKLINE BEECHAM PLC (GB) | 2001-07-24 | — | — | US | disclosed |
| EP-0912512-A1 | SULPHONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997048681-A1 | SULPHONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1997-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270455-A1 | Therapeutic agent for intestinal diseases and visceral pain | VIP, VIPR2, GPR17 | CARM1 4680/4885PRMT6 2921/4885PRMT1 3937/4885 |
| US-20050148632-A1 | Therapeutic agent for intestinal diseases and visceral pain | VIP, VIPR2, GPR17 | CARM1 4680/4885PRMT6 2921/4885PRMT1 3937/4885 |
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | CARM1 4394/4885PRMT6 2880/4885PRMT1 3039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.