Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24322571 | 1.00 | ACHE (0.43) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL4300726 | 0.95 | CARM1 (0.44) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL24322555 | 0.95 | CARM1 (0.44) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL4300723 | 0.95 | CARM1 (0.44) | ACHECARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL8333360 | 0.85 | CYP1A2 (0.46) | HRH3SIGMAR1CYP1A2CYP2D6HTR1A | |
| SCHEMBL18183309 | 0.84 | HTR1A (0.40) | HRH3SIGMAR1CYP1A2CYP2D6HTR1A | |
| SCHEMBL7961057 | 0.83 | CYP1A2 (0.48) | HRH3SIGMAR1CYP1A2CYP2D6HTR1A | |
| SCHEMBL4454573 | 0.83 | CYP1A2 (0.48) | HRH3SIGMAR1CYP1A2CYP2D6HTR1A | |
| SCHEMBL5683177 | 0.83 | CYP1A2 (0.48) | HRH3SIGMAR1CYP1A2CYP2D6HTR1A | |
| SCHEMBL4376304 | 0.82 | CYP2D6 (0.37) | HRH3SIGMAR1CYP1A2CYP2D6HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | ACHE 4649/4885CARM1 4394/4885PRMT6 2880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.