Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4300852 | 1.00 | ALDH1A1 (0.55) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL27990582 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL30679480 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL36926 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL36925 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL2474284 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL2474283 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| Hydrochloric Acid SCHEMBL29211442 | 0.83 | GPR35 (0.49) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL5362678 | 0.83 | TDP1 (0.55) | ALDH1A1TDP1RAB9ANPC1RECQL | |
| SCHEMBL4080273 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TDP1RAB9ANPC1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12224040-B2 | Movable type method applied to protein-ligand binding | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2025-02-11 | — | — | US | disclosed |
| US-20210317407-A1 | METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS | Seattle Children's Hospital (dba Seattle Children's Research Institute) | 2021-10-14 | — | — | US | disclosed |
| US-10332616-B2 | Movable type method applied to protein-ligand binding | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2019-06-25 | — | — | US | disclosed |
| US-20160350474-A1 | MOVABLE TYPE METHOD APPLIED TO PROTEIN-LIGAND BINDING | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-12-01 | — | — | US | disclosed |
| WO-2009126841-A1 | ENZYMATIC BIOSENSORS WITH ENHANCED ACTIVITY RETENTION FOR DETECTION OF ORGANIC COMPOUNDS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2009-10-15 | — | — | WO | disclosed |
| EP-1392825-A4 | PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 | COMMW SCIENT IND RES ORG (AU) | 2005-01-26 | — | — | EP | disclosed |
| EP-1392825-A1 | PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002092803-A1 | PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2002-11-21 | — | — | WO | disclosed |