Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.49 |
| ▸ | PPARA | Q07869 | 10/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23012852 | 0.85 | PPARG (0.55) | PPARGPPARAMEN1KMT2AKDM4E | |
| SCHEMBL29691478 | 0.85 | PPARG (0.55) | PPARGPPARAMEN1KMT2AKDM4E | |
| SCHEMBL10718327 | 0.83 | AKR1B1 (0.53) | PPARGPPARAMAOAMAOBMEN1 | |
| SCHEMBL1587813 | 0.77 | PPARG (0.41) | PPARGPPARAMAOAMAOBMEN1 | |
| SCHEMBL301328 | 0.77 | ALDH1A1 (0.61) | MEN1KMT2AMAPK1 | |
| SCHEMBL11551456 | 0.76 | PPARG (0.44) | PPARGPPARAMEN1KMT2AKDM4E | |
| SCHEMBL4298696 | 0.75 | PPARA (0.79) | PPARGPPARAMAPK1HTT | |
| SCHEMBL4301070 | 0.75 | PPARG (0.79) | PPARGPPARAFFAR1MAPK1 | |
| SCHEMBL3902642 | 0.74 | MAOA (0.50) | PPARGPPARAMAOAMAOBMEN1 | |
| SCHEMBL30198674 | 0.73 | APEX1 (0.65) | MAOAMAOBMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |