SCHEMBL4301192

SCHEMBL4301192

CCCCC(N)(OCCO)OCCO

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
SMPD1 P17405 3/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
THRB P10828 1/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 1/20 0.39
FDPS P14324 3/20 0.38
ALDH1A1 P00352 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
LMNA P02545 2/20 0.33
HSD17B10 Q99714 1/20 0.33
ACHE P22303 1/20 0.33
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4297349 0.94 SMPD1 (0.47) TSHRSMPD1MEN1KMT2ATHRB
SCHEMBL28066724 0.92 SMPD1 (0.50) TSHRSMPD1MEN1KMT2ATHRB
SCHEMBL9682320 0.92 SMPD1 (0.50) TSHRSMPD1MEN1KMT2ATHRB
SCHEMBL28066774 0.92 SMPD1 (0.50) TSHRSMPD1MEN1KMT2ATHRB
Hydrochloric Acid SCHEMBL8409535 0.90 SMPD1 (0.49) TSHRSMPD1MEN1KMT2ATHRB
SCHEMBL565548 0.86 TSHR (0.36) TSHRSMPD1MEN1KMT2ATHRB
SCHEMBL7238654 0.80 LMNA (0.48) TSHRSMPD1MEN1KMT2ATHRB
SCHEMBL16618735 0.77 SMPD1 (0.41) TSHRSMPD1FDPSLMNAADRB2
SCHEMBL565764 0.77 ALDH1A1 (0.38) TSHRMEN1KMT2ATHRBHTT
SCHEMBL4786958 0.74 TSHR (0.43) TSHRMEN1KMT2ATHRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230383157-A1 LOW FREE POLYURETHANE PREPOLYMER COMPOSITION FOR REACTIVE HOT MELT ADHESIVES LANXESS CORPORATION (US) 2023-11-30 US disclosed
EP-4214256-A1 LOW FREE POLYURETHANE PREPOLYMER COMPOSITION FOR REACTIVE HOT MELT ADHESIVES LANXESS Corporation (US) 2023-07-26 EP disclosed
US-20090266482-A1 HIGH-STRENGTH POLYURETHANE ADHESIVE HENKEL AG & CO. KGAA (DE) 2009-10-29 US disclosed
US-20080293872-A1 ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER HENKEL AG & CO. KGAA (DE) 2008-11-27 US disclosed
US-20080287574-A1 ADHESIVES, SEALANTS AND COATINGS CONTAINING GLASS PARTICLES AS A FILLER HENKEL AG & CO. KGAA (DE) 2008-11-20 US disclosed
US-20070117877-A1 Process for curing polyurethane adhesives/sealants HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2007-05-24 US disclosed
US-20060208858-A1 Method of coupling wireless portable communications device to electronicmail server by public wireless communications network when out of communication with private wireless communications GRIFFITH GREG 2006-09-21 US disclosed
US-20040259968-A1 Reactive polyurethanes having a low content of monomeric diisocyanates PARALLEL WIRELESS, INC. 2004-12-23 US disclosed
US-20040176522-A1 Adhesives/sealants with high electrical resistance HENKEL-TEROSON GMBH (DE) 2004-09-09 US disclosed
US-20040138402-A1 Two component polyurethane adhesive for wooden materials HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2004-07-15 US disclosed
US-20040126557-A1 Stone composite slabs HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-07-01 US disclosed
US-20040116545-A1 Two-component foam system for producing constructional foams and their use HILTI AKTIENGESELLSCHAFT (LI) 2004-06-17 US disclosed
US-20040115415-A1 Insulative stone composite slabs HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-06-17 US disclosed
US-20040010093-A1 UV-resistant flocking adhesive for polymeric substrates HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-01-15 US disclosed