Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301257 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDNPSR1HSD17B10 | |
| SCHEMBL4301256 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDNPSR1HSD17B10 | |
| SCHEMBL1732688 | 0.76 | MAPT (0.68) | ALDH1A1KDM4EHPGDNPSR1HSD17B10 | |
| SCHEMBL1732689 | 0.76 | MAPT (0.68) | ALDH1A1KDM4EHPGDNPSR1HSD17B10 | |
| SCHEMBL8350552 | 0.74 | KMT2A (0.72) | ALDH1A1KDM4EHPGDNPSR1HSD17B10 | |
| SCHEMBL1733385 | 0.73 | KDM4E (0.67) | ALDH1A1KDM4EHPGDNPSR1HSD17B10 | |
| SCHEMBL1733384 | 0.72 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDNPSR1HSD17B10 | |
| SCHEMBL3462643 | 0.71 | MEN1 (0.67) | ALDH1A1KDM4EHPGDNPSR1HSD17B10 | |
| SCHEMBL1733939 | 0.71 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDNPSR1HSD17B10 | |
| SCHEMBL1732832 | 0.70 | KDM4E (0.62) | ALDH1A1KDM4EHPGDNPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732486-A4 | DRUG-ENHANCED ADHESION PREVENTION | ETHICON INC (US) | 2009-04-08 | — | — | EP | claimed |
| JP-2007528391-A | — | — | 2007-10-11 | — | — | JP | claimed |
| EP-1732486-A1 | DRUG-ENHANCED ADHESION PREVENTION | ETHICON, INC. (US) | 2006-12-20 | — | — | EP | claimed |
| WO-2005092264-A1 | DRUG-ENHANCED ADHESION PREVENTION | ETHICON, INC. (US) | 2005-10-06 | — | — | WO | claimed |