Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | STAT1 | P42224 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1732688 | 1.00 | MAPT (0.68) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL1733385 | 0.81 | KDM4E (0.67) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL1732832 | 0.78 | KDM4E (0.62) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL7482289 | 0.77 | KDM4E (0.65) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7486758 | 0.76 | LMNA (0.69) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL2849002 | 0.76 | MEN1 (1.00) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL2839312 | 0.76 | MEN1 (1.00) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL1732760 | 0.76 | KDM4E (0.60) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL4301252 | 0.76 | ALDH1A1 (0.53) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6785270 | 0.76 | MAPT (0.78) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9066912-B2 | Drug-enhanced adhesion prevention | ETHICON, INC. (US) | 2015-06-30 | — | — | US | claimed |
| EP-1732486-B1 | TRANILAST COMPOSITION FOR USE IN THE PREVENTION OF POSTOPERATIVE ADHESION | ETHICON INC (US) | 2014-05-07 | — | — | EP | claimed |
| EP-2035008-B1 | COMPOSITIONS AND METHODS FOR PREVENTING OR REDUCING POSTOPERATIVE ILEUS AND GASTRIC STASIS IN MAMMALS | ETHICON INC (US) | 2011-11-23 | — | — | EP | claimed |
| EP-1732486-A4 | DRUG-ENHANCED ADHESION PREVENTION | ETHICON INC (US) | 2009-04-08 | — | — | EP | claimed |
| JP-2007528391-A | — | — | 2007-10-11 | — | — | JP | claimed |
| EP-1732486-A1 | DRUG-ENHANCED ADHESION PREVENTION | ETHICON, INC. (US) | 2006-12-20 | — | — | EP | claimed |
| WO-2005092264-A1 | DRUG-ENHANCED ADHESION PREVENTION | ETHICON, INC. (US) | 2005-10-06 | — | — | WO | claimed |
| US-20050106230-A1 | Drug-enhanced adhesion prevention | ETHICON, INC. | 2005-05-19 | — | — | US | claimed |
| US-20050106229-A1 | Drug-enhanced adhesion prevention | ETHICON, INC. | 2005-05-19 | — | — | US | claimed |
| US-9066912-B2 | Drug-enhanced adhesion prevention | ETHICON, INC. (US) | 2015-06-30 | — | — | US | disclosed |
| EP-1732486-B1 | TRANILAST COMPOSITION FOR USE IN THE PREVENTION OF POSTOPERATIVE ADHESION | ETHICON INC (US) | 2014-05-07 | — | — | EP | disclosed |
| EP-2035008-B1 | COMPOSITIONS AND METHODS FOR PREVENTING OR REDUCING POSTOPERATIVE ILEUS AND GASTRIC STASIS IN MAMMALS | ETHICON INC (US) | 2011-11-23 | — | — | EP | disclosed |
| EP-1732486-A4 | DRUG-ENHANCED ADHESION PREVENTION | ETHICON INC (US) | 2009-04-08 | — | — | EP | disclosed |
| EP-1732486-A1 | DRUG-ENHANCED ADHESION PREVENTION | ETHICON, INC. (US) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092264-A1 | DRUG-ENHANCED ADHESION PREVENTION | ETHICON, INC. (US) | 2005-10-06 | — | — | WO | disclosed |
| US-20050106230-A1 | Drug-enhanced adhesion prevention | ETHICON, INC. | 2005-05-19 | — | — | US | disclosed |
| US-20050106229-A1 | Drug-enhanced adhesion prevention | ETHICON, INC. | 2005-05-19 | — | — | US | disclosed |