Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.77 |
| ▸ | FOS | P01100 | 2/20 | 0.67 |
| ▸ | JUN | P05412 | 2/20 | 0.67 |
| ▸ | GSK3B | P49841 | 7/20 | 0.64 |
| ▸ | BACE1 | P56817 | 7/20 | 0.64 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608059 | 1.00 | CYP1A2 (0.77) | CYP1A2FOSJUNGSK3BBACE1 | |
| SCHEMBL608060 | 1.00 | CYP1A2 (0.77) | CYP1A2FOSJUNGSK3BBACE1 | |
| SCHEMBL26382466 | 0.87 | CYP1A2 (1.00) | CYP1A2JUNTRPV1SMN1; SMN2MAPT | |
| SCHEMBL20586571 | 0.83 | CYP1A2 (0.77) | CYP1A2FOSJUNGSK3BBACE1 | |
| SCHEMBL610560 | 0.83 | CYP1A2 (0.77) | CYP1A2FOSJUNGSK3BBACE1 | |
| SCHEMBL610559 | 0.83 | CYP1A2 (0.77) | CYP1A2FOSJUNGSK3BBACE1 | |
| SCHEMBL846833 | 0.82 | CYP1A2 (0.75) | CYP1A2TRPV1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL4001354 | 0.82 | CYP1A2 (0.75) | CYP1A2TRPV1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL818742 | 0.82 | CYP1A2 (0.75) | CYP1A2TRPV1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL608506 | 0.80 | FOS (1.00) | CYP1A2FOSJUNGSK3BBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090263492-A1 | Diagnostic Methods and Genetic Markers for Alzheimer Disease | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2009-10-22 | — | — | US | claimed |
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-02-16 | — | — | US | disclosed |
| US-20090263492-A1 | Diagnostic Methods and Genetic Markers for Alzheimer Disease | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090263492-A1 | Diagnostic Methods and Genetic Markers for Alzheimer Disease | CHAT, SLC18A3, GAP43 | CYP1A2 2261/4885FOS 4099/4885JUN 4432/4885 |
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | L1CAM, LY96, GMFG | CYP1A2 4526/4885FOS 4116/4885JUN 4222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.