SCHEMBL4301326

SCHEMBL4301326

C[Si](C)(C)c1ccc([Si](C)(C)C)c(O)c1O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
ESR1 P03372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3119798 0.81 ALDH1A1 (0.41) ALDH1A1ESR1
SCHEMBL18604569 0.75 ALDH1A1 (0.52) ALDH1A1
SCHEMBL1142750 0.74 PTPN22 (0.54) ALDH1A1
SCHEMBL18604570 0.73 TDP1 (0.32) ALDH1A1
SCHEMBL13318424 0.73 ALDH1A1 (0.59) ALDH1A1
SCHEMBL4304730 0.73 NR1H2 (0.39) ESR1
SCHEMBL5090209 0.72 IDO1 (0.34) ALDH1A1
SCHEMBL10706871 0.69 CA2 (0.46) ALDH1A1
SCHEMBL5596281 0.69 IDO1 (0.36) ALDH1A1
SCHEMBL4301324 0.68 ESR1 (0.58) ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009027541-A2 OXYGEN COMPOUNDS OF THE BORON GROUP CHEMETALL GMBH (DE) 2009-03-05 WO disclosed