Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HK1 | P19367 | 2/20 | 0.44 |
| ▸ | HK2 | P52789 | 2/20 | 0.44 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GALK1 | P51570 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacinamide SCHEMBL28184048 | 0.86 | F7 (0.48) | MAOBPOLB | |
| Niacinamide SCHEMBL30498617 | 0.86 | F7 (0.48) | MAOBPOLB | |
| Ribose (Furanose) SCHEMBL502653 | 0.81 | HK1 (0.53) | HK1HK2KDM4EPOLBMAPT | |
| SCHEMBL17554435 | 0.81 | FBP1 (0.46) | GAA | |
| SCHEMBL4009422 | 0.81 | FBP1 (0.46) | GAA | |
| SCHEMBL216723 | 0.81 | FBP1 (0.46) | GAA | |
| SCHEMBL1931658 | 0.81 | FBP1 (0.46) | GAA | |
| SCHEMBL14783446 | 0.81 | FBP1 (0.46) | GAA | |
| SCHEMBL6670386 | 0.81 | FBP1 (0.46) | GAA | |
| SCHEMBL502386 | 0.81 | FBP1 (0.46) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268575-B2 | NAD biosynthesis systems | WASHINGTON UNIVERSITY (US) | 2012-09-18 | — | — | US | disclosed |
| US-20090246803-A1 | NAD BIOSYNTHESIS SYSTEMS | WASHINGTON UNIVERSITY (US) | 2009-10-01 | — | — | US | disclosed |
| WO-2006041624-A2 | NAD BIOSYNTHESIS SYSTEMS | WASHINGTON UNIVERSITY (US) | 2006-04-20 | — | — | WO | disclosed |