Niacinamide

Niacinamide

SCHEMBL28184048

NC(=O)c1cccnc1.O=P(O)(O)OC1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ F7 P08709 1/20 0.48
▸ F3 P13726 1/20 0.48
▸ SARM1 Q6SZW1 1/20 0.48
▸ SIRT2 Q8IXJ6 1/20 0.48
▸ SIRT6 Q8N6T7 1/20 0.48
▸ SIRT1 Q96EB6 1/20 0.48
▸ SIRT3 Q9NTG7 1/20 0.48
▸ SIRT5 Q9NXA8 1/20 0.48
▸ SIRT4 Q9Y6E7 1/20 0.48
▸ CDK1 P06493 1/20 0.40
▸ CDK4 P11802 1/20 0.40
▸ CCNB1 P14635 1/20 0.40
▸ CCND1 P24385 1/20 0.40
▸ SLC5A1 P13866 1/20 0.38
▸ SLC5A2 P31639 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ SLC28A3 Q9HAS3 2/20 0.38
▸ THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Niacinamide SCHEMBL30498617 1.00 F7 (0.48) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL3915026 0.92 F7 (0.44) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL28671370 0.92 F7 (0.46) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL3907994 0.90 F7 (0.42) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL20398298 0.89 F7 (0.55) F7F3SARM1SIRT2SIRT6
Benzamide SCHEMBL4301755 0.86 MAOB (0.46) POLBMAOB
Niacinamide SCHEMBL28136690 0.85 F7 (0.51) F7F3SARM1SIRT2SIRT6
Ribose (Furanose) SCHEMBL17315030 0.85 F7 (0.54) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL17315028 0.84 F7 (0.50) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL21571784 0.84 F7 (0.50) F7F3SARM1SIRT2SIRT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119736324-A NMN efficient synthetic strain, construction method and production application thereof 天津大学 2025-04-01 — — CN claimed
CN-119193443-A Recombinant escherichia coli for producing NMN through fermentation and application thereof 江南大学 2024-12-27 — — CN claimed
CN-119193449-A Recombinant escherichia coli for producing NMN as well as preparation method and application thereof 华熙生物科技股份有限公司 2024-12-27 — — CN claimed
CN-118434765-A BCMA monoclonal antibodies and antibody-drug conjugates 杭州多禧生物科技有限公司 2024-08-02 — — CN claimed
CN-112654608-B Fused ring compound having urea structure 桑福德伯纳姆普利斯医学发现研究所 2024-05-07 — — CN claimed
CN-117126756-B Construction method and application of recombinant strain for preparing nicotinamide phosphoribosyl transferase 中国科学院天津工业生物技术研究所 2024-03-12 — — CN claimed
CN-117479933-A Compounds for the treatment of neurodegenerative disorders, degenerative disorders and metabolic disorders and uses thereof 佛罗里达大学研究基金会公司 2024-01-30 — — CN claimed
CN-117126756-A Construction method and application of recombinant strain for preparing nicotinamide phosphoribosyl transferase 中国科学院天津工业生物技术研究所 2023-11-28 — — CN claimed
CN-110945128-B Compositions and methods for treating pulmonary fibrosis 代表亚利桑那大学的亚利桑那董事会 2023-11-03 — — CN claimed
CN-116004489-A Recombinant escherichia coli for producing NMN and application thereof 华熙生物科技股份有限公司 2023-04-25 — — CN claimed
CN-116004743-A Method and carrier for synthesizing nicotinamide mononucleotide by bacteria 常州大学 2023-04-25 — — CN claimed
CN-122005838-A CD 38-targeted antibody-drug conjugate and preparation method and application thereof 上海科技大学 2026-05-12 — — CN disclosed
CN-121378112-A Application of NAD+ supplementing prodrug in preventing and treating abdominal aortic aneurysm 中国人民解放军海军军医大学 2026-01-23 — — CN disclosed
CN-120137933-A Polyphosphatase mutant and application thereof in synthesis of beta-nicotinamide mononucleotide 浙江工业大学 2025-06-13 — — CN disclosed
CN-120060196-A Development of novel energy system and application of novel energy system in conversion of one-carbon substrate 江南大学 2025-05-30 — — CN disclosed
CN-113122594-B Method for preparing mononucleotide of nicotinic acid or derivative thereof and biological product thereof 百瑞全球有限公司 2023-04-25 — — CN disclosed
CN-116004489-A Recombinant escherichia coli for producing NMN and application thereof 华熙生物科技股份有限公司 2023-04-25 — — CN disclosed
CN-113106080-B Nicotinamide phosphoribosyl transferase mutant and application thereof 深圳希吉亚生物技术有限公司 2022-02-25 — — CN disclosed
CN-107557412-B Method for catalytically synthesizing NADPH by immobilized enzyme 苏州人本药业有限公司 2020-02-28 — — CN disclosed
CN-107557412-A A kind of immobilized enzyme catalysis synthesis NADPH method 苏州人本药业有限公司 2018-01-09 — — CN disclosed
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