Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | LDHB | P07195 | 1/20 | 0.31 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4300666 | 0.94 | ALDH1A1 (0.53) | ALDH1A1TSHRTP53MDM2SMN1; SMN2 | |
| SCHEMBL4299568 | 0.90 | ALDH1A1 (0.59) | ALDH1A1TSHRTP53MDM2SMN1; SMN2 | |
| Aes-103 SCHEMBL4301948 | 0.87 | ALDH1A1 (0.71) | ALDH1A1TSHRTP53SMN1; SMN2NPC1 | |
| SCHEMBL18066379 | 0.87 | ALDH1A1 (0.56) | ALDH1A1TSHRTP53MDM2SMN1; SMN2 | |
| SCHEMBL17693406 | 0.86 | ALDH1A1 (0.57) | ALDH1A1TSHRTP53MDM2SMN1; SMN2 | |
| SCHEMBL135809 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TSHRTP53MDM2SMN1; SMN2 | |
| SCHEMBL278333 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TSHRTP53MDM2SMN1; SMN2 | |
| Aes-103 SCHEMBL4300664 | 0.81 | ALDH1A1 (0.67) | ALDH1A1TSHRTP53SMN1; SMN2NPC1 | |
| SCHEMBL25207012 | 0.81 | ALDH1A1 (0.45) | ALDH1A1TSHRTP53MDM2SMN1; SMN2 | |
| SCHEMBL1664842 | 0.81 | ALDH1A1 (0.45) | ALDH1A1TSHRTP53MDM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2033958-A1 | Hydroxymethylfurfural ethers from sugars and di- and triols | Furanix Technologies B.V (NL) | 2009-03-11 | — | — | EP | claimed |