SCHEMBL278333

SCHEMBL278333

O=Cc1ccc(COCc2ccc(C=O)o2)o1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.61
TSHR P16473 1/20 0.61
L3MBTL1 Q9Y468 2/20 0.41
HTT P42858 1/20 0.41
GAA P10253 1/20 0.41
TP53 P04637 2/20 0.39
MDM2 Q00987 1/20 0.39
KDM4E B2RXH2 8/20 0.37
POLB P06746 4/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 4/20 0.35
RAB9A P51151 3/20 0.35
NPC1 O15118 2/20 0.35
HSP90AA1 P07900 1/20 0.35
HPGD P15428 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
CYP2E1 P05181 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17693406 0.92 ALDH1A1 (0.57) ALDH1A1TSHRL3MBTL1HTTGAA
SCHEMBL10374139 0.89 ALDH1A1 (0.50) ALDH1A1TSHRL3MBTL1HTTGAA
SCHEMBL22289462 0.88 TSHR (0.50) ALDH1A1TSHRL3MBTL1TP53MDM2
SCHEMBL17477708 0.86 ALDH1A1 (0.51) ALDH1A1TSHRL3MBTL1HTTTP53
SCHEMBL18523408 0.85 ALDH1A1 (0.50) ALDH1A1TSHRL3MBTL1HTTGAA
SCHEMBL4299568 0.85 ALDH1A1 (0.59) ALDH1A1TSHRL3MBTL1HTTGAA
SCHEMBL19248450 0.85 POLB (0.52) ALDH1A1TSHRL3MBTL1KDM4EPOLB
SCHEMBL1664017 0.84 ALDH1A1 (0.49) ALDH1A1TSHRL3MBTL1HTTGAA
SCHEMBL19670017 0.84 ALDH1A1 (0.49) ALDH1A1TSHRL3MBTL1HTTGAA
SCHEMBL14433356 0.83 ALDH1A1 (0.57) ALDH1A1TSHRL3MBTL1HTTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120025298-A Bis- (5-formylfurfuryl) ether and preparation method thereof 合肥利夫生物科技有限公司 2025-05-23 CN claimed
CN-119775232-A Preparation method of bis- (5-hydroxymethyl furfuryl) ether 中科国生(泰兴)新材料科技有限公司 2025-04-08 CN claimed
CN-119775515-A Biomass-based polyfuran polymer material and preparation method thereof 常州大学 2025-04-08 CN claimed
CN-119661482-A Preparation method of 5,5' - [ oxybis (methylene) ] bis [ 2-furancarboxylic acid ] compound 浙江糖能科技有限公司 2025-03-21 CN claimed
CN-119552134-A Method for separating and purifying bis- (5-formylfurfuryl) ether from 5-hydroxymethylfurfural crude product 中国科学院宁波材料技术与工程研究所 2025-03-04 CN claimed
CN-119555819-A Method for simultaneously measuring content of 5-hydroxymethylfurfural and bis- (5-formylfurfuryl) ether 中国科学院宁波材料技术与工程研究所 2025-03-04 CN claimed
CN-118930503-A Purification method and application of 2, 5-furandicarboxylic acid composition 浙江糖能科技有限公司 2024-11-12 CN claimed
CN-117700381-A Method for preparing bis- (5-formylfurfuryl) ether by catalyzing 5-hydroxymethylfurfural with ionic liquid catalyst 中国科学院大连化学物理研究所 2024-03-15 CN claimed
CN-117603171-A Preparation method of bis- (5-carboxyl furfuryl) ether 中科国生(杭州)科技有限公司 2024-02-27 CN claimed
CN-117050039-A Preparation method of bis- (5-hydroxymethyl furfuryl) ether 中科国生(杭州)科技有限公司 2023-11-14 CN claimed
WO-2019156483-A1 METHOD FOR PRODUCING FUNCTIONAL CRYSTALLINE SWEETENER 주식회사 삼양사 2019-08-15 WO claimed
US-20180215724-A1 PROCESS FOR PREPARING FURAN-2,5-DICARBOXYLIC ACID BASF SE (DE) 2018-08-02 US claimed
EP-3325457-A1 PROCESS FOR PREPARING FURAN-2,5-DICARBOXYLIC ACID BASF SE (DE) 2018-05-30 EP claimed
WO-2017012842-A1 PROCESS FOR PREPARING FURAN-2,5-DICARBOXYLIC ACID BASF SE (DE) 2017-01-26 WO claimed
WO-2016207025-A1 METHOD FOR SYNTHESIZING AND SEPARATING HMF BASF SE (DE) 2016-12-29 WO claimed
EP-2197867-B1 HYDROXYMETHYLFURFURAL ETHERS FROM SUGARS OR HMF AND BRANCHED ALCOHOLS FURANIX TECHNOLOGIES BV (NL) 2016-03-02 EP claimed
EP-2197868-B1 HYDROXYMETHYLFURFURAL ETHERS FROM SUGARS OR HMF AND MIXED ALCOHOLS FURANIX TECHNOLOGIES BV (NL) 2011-04-27 EP claimed
EP-2197868-A2 HYDROXYMETHYLFURFURAL ETHERS FROM SUGARS OR HMF AND MIXED ALCOHOLS Furanix Technologies B.V (NL) 2010-06-23 EP claimed
US-20100058650-A1 For example, 5-ethoxymethylfurfural; use of mixed alcohols in reaction mixture to prevent product crystallization; end use as renewable biofuel or fuel additive, or as renewable raw material to make monomers such as furandicarboxylic acid FURANIX TECHNOLOGIES B.V. (NL) 2010-03-11 US claimed
WO-2009030508-A2 HYDROXYMETHYLFURFURAL ETHERS FROM SUGARS OR HMF AND MIXED ALCOHOLS FURANIX TECHNOLOGIES B.V. (NL) 2009-03-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180215724-A1 PROCESS FOR PREPARING FURAN-2,5-DICARBOXYLIC ACID HAO2, HMOX2, HPD ALDH1A1 763/4885TSHR 4608/4885L3MBTL1 4507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.