Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301965 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AATMKMT2A | |
| SCHEMBL4301962 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AATMKMT2A | |
| SCHEMBL27615293 | 0.78 | SMN1; SMN2 (0.75) | SMN1; SMN2NPC1RAB9AATMEPHX1 | |
| SCHEMBL4309071 | 0.73 | MMP2 (0.48) | SMN1; SMN2NPC1RAB9AATMKMT2A | |
| SCHEMBL4309069 | 0.73 | MMP2 (0.48) | SMN1; SMN2NPC1RAB9AATMKMT2A | |
| SCHEMBL4309076 | 0.73 | MMP2 (0.48) | SMN1; SMN2NPC1RAB9AATMKMT2A | |
| SCHEMBL2272372 | 0.68 | EPHX2 (0.55) | SMN1; SMN2NPC1RAB9AKMT2ACHRNA7 | |
| SCHEMBL17600488 | 0.67 | BCHE (0.66) | — | |
| SCHEMBL16293726 | 0.67 | BCHE (0.66) | — | |
| SCHEMBL76489 | 0.67 | ALDH1A1 (0.67) | SMN1; SMN2NPC1RAB9AKMT2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090075840-A1 | Methods And Compositions For Generating Mixtures Of Nucleic Acid Molecules | AGILENT TECHNOLOGIES, INC. | 2009-03-19 | — | — | US | disclosed |