Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.34 |
| ▸ | PLG | P00747 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 4/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 3/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 2/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302600 | 0.81 | PARP1 (0.34) | — | |
| SCHEMBL2229900 | 0.78 | — | — | |
| SCHEMBL6160094 | 0.71 | TLR9 (0.36) | GABRA1GABRG2GABRB3PLGHTR1A | |
| SCHEMBL4301470 | 0.66 | MAPT (0.34) | GABRA1GABRG2GABRB3PLGHTR1A | |
| SCHEMBL4303824 | 0.63 | TNKS (0.37) | GABRA1GABRG2GABRB3PLGMAPT | |
| SCHEMBL23216734 | 0.62 | QDPR (0.45) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29768468 | 0.62 | QDPR (0.45) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL788535 | 0.62 | QDPR (0.45) | MAPTTHRBTNKSTNKS2 | |
| SCHEMBL30232420 | 0.61 | SLC6A2 (0.46) | GABRA1GABRG2GABRB3PLGHTR1A | |
| SCHEMBL4959377 | 0.60 | MAPKAPK2 (0.36) | GABRA1GABRG2GABRB3PLGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009124882-A1 | NOVEL PIPERIDINYL-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONES AS M1 AGONISTS | H. LUNDBECK A/S (DK) | 2009-10-15 | — | — | WO | disclosed |
| WO-2009124883-A1 | NOVEL 1,3-DIHYDRO-BENZOIMIDAZOL-2-ONES AS M1 AGONISTS | H. LUNDBECK A/S (DK) | 2009-10-15 | — | — | WO | disclosed |