Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 5/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.33 |
| ▸ | PLG | P00747 | 2/20 | 0.33 |
| ▸ | PLAT | P00750 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160094 | 0.83 | TLR9 (0.36) | MAPTTHRBHTR1ASLC6A2SLC6A4 | |
| SCHEMBL788535 | 0.74 | QDPR (0.45) | MAPTTHRBHTR6HTR2C | |
| SCHEMBL4959377 | 0.71 | MAPKAPK2 (0.36) | MAPTTHRBGABRA1GABRG2GABRB3 | |
| SCHEMBL6204472 | 0.66 | MPO (0.35) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4301980 | 0.66 | GABRA1 (0.34) | MAPTTHRBHTR1ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL5720133 | 0.63 | HPGD (0.40) | KMT2A | |
| SCHEMBL3385674 | 0.63 | SLC6A2 (0.52) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL4303824 | 0.63 | TNKS (0.37) | MAPTTHRBGABRA1GABRG2GABRB3 | |
| SCHEMBL4960528 | 0.63 | HTR2C (0.39) | MAPTTHRBGABRA1GABRG2GABRB3 | |
| SCHEMBL7367981 | 0.63 | GRIN2D (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3644995-A1 | DEUTERATED DOMPERIDONE COMPOSITIONS, METHODS, AND PREPARATION | CinDome Pharma, Inc. (US) | 2020-05-06 | — | — | EP | disclosed |
| WO-2019006078-A1 | DEUTERATED DOMPERIDONE COMPOSITIONS, METHODS, AND PREPARATION | CINRX PHARMA, LLC (US) | 2019-01-03 | — | — | WO | disclosed |
| WO-2009124882-A1 | NOVEL PIPERIDINYL-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONES AS M1 AGONISTS | H. LUNDBECK A/S (DK) | 2009-10-15 | — | — | WO | disclosed |
| WO-2009124883-A1 | NOVEL 1,3-DIHYDRO-BENZOIMIDAZOL-2-ONES AS M1 AGONISTS | H. LUNDBECK A/S (DK) | 2009-10-15 | — | — | WO | disclosed |
| EP-2032142-A2 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007147109-A2 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |
| EP-1866311-A2 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006104889-A2 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2006-10-05 | — | — | WO | disclosed |
| EP-1451173-A4 | PIPERIDINES | ICAGEN INC (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1451173-A2 | PIPERIDINES | Icagen, Inc. (US) | 2004-09-01 | — | — | EP | disclosed |
| EP-1373248-A1 | BENZIMIDAZOL DERIVATIVES MODULATE CHEMOKINE RECEPTORS | AstraZeneca AB (SE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2003037890-A2 | PIPERIDINES | ICAGEN, INC. (US) | 2003-05-08 | — | — | WO | disclosed |
| WO-2002074763-A9 | BENZIMIDAZOL DERIVATIVES MODULATE CHEMOKINE RECEPTORS | ASTRAZENECA AB (SE) | 2002-10-24 | — | — | WO | disclosed |
| WO-2002074763-A1 | BENZIMIDAZOL DERIVATIVES MODULATE CHEMOKINE RECEPTORS | ASTRAZENECA AB (SE) | 2002-09-26 | — | — | WO | disclosed |