Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664773 | 0.83 | MAPT (0.38) | MAPTLMNAKDM4EMGAMGAA | |
| SCHEMBL29021009 | 0.82 | MAPT (0.37) | MAPTLMNAKDM4EMGAMGAA | |
| SCHEMBL2912395 | 0.82 | CPA1 (0.45) | MAPTLMNAKDM4EMGAMGAA | |
| SCHEMBL1228652 | 0.82 | CPA1 (0.45) | MAPTLMNAKDM4EMGAMGAA | |
| SCHEMBL1410099 | 0.82 | CPA1 (0.45) | MAPTLMNAKDM4EMGAMGAA | |
| SCHEMBL5105701 | 0.81 | TSHR (0.41) | MAPTLMNAKDM4EMGAMGAA | |
| SCHEMBL3121387 | 0.80 | KDM4E (0.39) | MAPTLMNAKDM4EMGAMGAA | |
| SCHEMBL5492736 | 0.78 | CYP2D6 (0.35) | MAPTLMNAKDM4EMGAMGAA | |
| SCHEMBL29632440 | 0.78 | TLR4 (0.41) | MAPTLMNAKDM4EALDH1A1TSHR | |
| SCHEMBL17079711 | 0.78 | TLR4 (0.41) | MAPTLMNAKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038412-A2 | BETA-SECRETASE INHIBITING COMPOUNDS | LG LIFE SCIENCES, LTD. (KR) | 2009-03-26 | — | — | WO | disclosed |