Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28008704 | 0.93 | FFAR1 (0.53) | FFAR1ALDH1A1MAPK1L3MBTL1PPARG | |
| SCHEMBL1508345 | 0.86 | FFAR1 (0.49) | FFAR1ALDH1A1PPARG | |
| SCHEMBL3821109 | 0.81 | FFAR1 (0.51) | FFAR1ALDH1A1 | |
| SCHEMBL1882562 | 0.80 | ALDH1A1 (0.54) | FFAR1LMNAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL1508431 | 0.80 | FFAR1 (0.46) | FFAR1PPARG | |
| SCHEMBL10316924 | 0.79 | FFAR1 (0.62) | FFAR1PPARG | |
| SCHEMBL4031828 | 0.79 | FFAR1 (0.62) | FFAR1PPARG | |
| SCHEMBL16408022 | 0.77 | ALDH1A1 (0.51) | FFAR1LMNAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL27731969 | 0.77 | SLC15A1 (0.52) | LMNAALDH1A1MAPK1L3MBTL1SLC15A1 | |
| SCHEMBL28008254 | 0.75 | FFAR1 (0.50) | FFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125711-A1 | 2 -SUBSTITUTED- 3 -PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | Albireo Ab (SE) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008108735-A1 | 2 -SUBSTITUTED- 3 -PHENYLPROPIONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | ALBIREO AB (SE) | 2008-09-12 | — | — | WO | disclosed |