Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.46 |
| ▸ | MASP2 | O00187 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4314574 | 0.85 | MASP2 (0.48) | NAMPTMASP2HDAC1GABRPGABRD | |
| SCHEMBL4309515 | 0.85 | MASP2 (0.48) | NAMPTMASP2HDAC1CARM1PRMT6 | |
| SCHEMBL4309444 | 0.85 | NAMPT (0.47) | NAMPTMASP2HDAC1GABRPGABRD | |
| SCHEMBL4309556 | 0.82 | NAMPT (0.44) | NAMPTMASP2HDAC1TRPV1ALDH1A1 | |
| SCHEMBL4308881 | 0.82 | NAMPT (0.44) | NAMPTMASP2HDAC1GABRPGABRD | |
| SCHEMBL4303439 | 0.82 | NAMPT (0.53) | NAMPTMASP2HDAC1GABRPGABRD | |
| SCHEMBL1431844 | 0.80 | MASP2 (0.45) | NAMPTMASP2HDAC1CARM1PRMT6 | |
| SCHEMBL1905450 | 0.80 | MASP2 (0.43) | NAMPTMASP2HDAC1CARM1PRMT6 | |
| SCHEMBL4313075 | 0.80 | F2 (0.51) | MASP2 | |
| SCHEMBL1904477 | 0.79 | MASP2 (0.42) | NAMPTMASP2HDAC1CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |