Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 3/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 2/20 | 0.37 |
| ▸ | METAP1 | P53582 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | TARS1 | P26639 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1905450 | 0.90 | MASP2 (0.43) | MASP2CARM1PRMT6HDAC1NAMPT | |
| SCHEMBL1901038 | 0.88 | MASP2 (0.44) | MASP2CARM1PRMT6HDAC1NAMPT | |
| SCHEMBL1901851 | 0.86 | MASP2 (0.41) | MASP2CARM1PRMT6HDAC1NAMPT | |
| SCHEMBL1904477 | 0.85 | MASP2 (0.42) | MASP2CARM1PRMT6HDAC1NAMPT | |
| SCHEMBL1901410 | 0.84 | MASP2 (0.41) | MASP2HDAC1NAMPTMETAP2METAP1 | |
| SCHEMBL1432468 | 0.83 | CYP3A4 (0.42) | MASP2CARM1PRMT6HDAC1NAMPT | |
| SCHEMBL4303211 | 0.80 | NAMPT (0.46) | MASP2CARM1PRMT6HDAC1NAMPT | |
| SCHEMBL3154370 | 0.78 | MASP2 (0.47) | MASP2CARM1PRMT6 | |
| SCHEMBL3154337 | 0.78 | MASP2 (0.47) | MASP2CARM1PRMT6 | |
| SCHEMBL1907939 | 0.76 | METAP2 (0.37) | CARM1PRMT6HDAC1METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |