Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | FADS1 | O60427 | 3/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4303560 | 0.80 | NOTUM (0.38) | NOTUMALOX5 | |
| SCHEMBL6984473 | 0.79 | NOTUM (0.53) | NOTUMDRD2DRD3ALOX5FADS1 | |
| SCHEMBL9105102 | 0.79 | NOTUM (0.53) | NOTUMDRD2DRD3ALOX5FADS1 | |
| SCHEMBL6991769 | 0.78 | NOTUM (0.49) | NOTUMDRD2DRD3ALOX5FADS1 | |
| SCHEMBL6839730 | 0.75 | DRD2 (0.52) | NOTUMDRD2DRD3ALOX5NSD2 | |
| SCHEMBL6985886 | 0.74 | NOTUM (0.60) | NOTUMDRD2DRD3ALOX5NSD2 | |
| SCHEMBL6988378 | 0.72 | NOTUM (0.57) | NOTUMDRD2DRD3ALOX5 | |
| SCHEMBL14632427 | 0.72 | NOTUM (0.57) | NOTUMDRD2DRD3ALOX5 | |
| SCHEMBL6988377 | 0.72 | FADS1 (0.55) | NOTUMFADS1NSD2 | |
| SCHEMBL22241342 | 0.71 | MEN1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176465-A1 | Cyclic amino acid derivatives | MERCK PATENT GMBH (DE) | 2003-09-18 | — | — | US | disclosed |
| EP-1301506-A1 | CYCLIC AMINO ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006269-A1 | CYCLIC AMINO ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176465-A1 | Cyclic amino acid derivatives | F5, F11, F2 | NOTUM 4067/4885DRD2 3651/4885DRD3 3576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.