Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MGAM | O43451 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4312684 | 0.83 | MGAM (0.56) | SMN1; SMN2HTTMGAMCNR2MAPT | |
| SCHEMBL4606005 | 0.81 | MGAM (0.61) | SMN1; SMN2HTTMGAMCNR2MAPT | |
| SCHEMBL3396288 | 0.81 | MGAM (0.53) | SMN1; SMN2HTTMGAMCNR2MAPT | |
| SCHEMBL3954441 | 0.80 | MGAM (0.66) | SMN1; SMN2MGAMCNR2MAPTKDM4E | |
| SCHEMBL5176927 | 0.79 | MGAM (0.63) | SMN1; SMN2MGAMCNR2MAPTKDM4E | |
| SCHEMBL6955948 | 0.79 | MGAM (0.63) | SMN1; SMN2MGAMCNR2MAPTKDM4E | |
| SCHEMBL4859653 | 0.78 | MGAM (0.54) | SMN1; SMN2HTTMGAMCNR2MAPT | |
| Trifluoroacetic Acid SCHEMBL28462831 | 0.78 | MGAM (0.54) | SMN1; SMN2HTTMGAMCNR2MAPT | |
| SCHEMBL4302912 | 0.77 | MGAM (0.61) | SMN1; SMN2MGAMCNR2MAPTKDM4E | |
| SCHEMBL725183 | 0.77 | MGAM (0.61) | SMN1; SMN2HTTMGAMCNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024272-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | Renovis, Inc. (US) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007133637-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | RENOVIS, INC. (US) | 2007-11-22 | — | — | WO | disclosed |