Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 8/20 | 0.76 |
| ▸ | HRH1 | P35367 | 2/20 | 0.62 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18248629 | 0.98 | TBXAS1 (0.77) | TBXAS1HRH1CYP2A6TDP1L3MBTL1 | |
| SCHEMBL14959999 | 0.98 | TBXAS1 (0.77) | TBXAS1HRH1CYP2A6TDP1L3MBTL1 | |
| SCHEMBL10772829 | 0.98 | TBXAS1 (0.77) | TBXAS1HRH1CYP2A6TDP1L3MBTL1 | |
| SCHEMBL933853 | 0.95 | TBXAS1 (0.68) | TBXAS1HRH1CYP2A6TDP1L3MBTL1 | |
| SCHEMBL18248504 | 0.90 | TBXAS1 (0.65) | TBXAS1HRH1CYP2A6TDP1L3MBTL1 | |
| SCHEMBL18248608 | 0.90 | TBXAS1 (0.65) | TBXAS1HRH1CYP2A6TDP1L3MBTL1 | |
| SCHEMBL83186 | 0.89 | RECQL (0.62) | TBXAS1HRH1CYP2A6RECQLCHRNA7 | |
| Hydrochloric Acid SCHEMBL5349530 | 0.88 | TBXAS1 (0.61) | TBXAS1HRH1CYP2A6RECQLCHRNA7 | |
| SCHEMBL18248525 | 0.87 | TBXAS1 (0.62) | TBXAS1HRH1CYP2A6RECQLMAPT | |
| SCHEMBL744045 | 0.86 | TBXAS1 (1.00) | TBXAS1HRH1CYP2A6TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009126675-A1 | 2-SULFONYLAMINO-4-HETEROARYL BUTYRAMIDE ANTAGONISTS OF CCR10 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-15 | — | — | WO | disclosed |
| US-4551460-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1985-11-05 | — | — | US | disclosed |