Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.68 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | HRH1 | P35367 | 2/20 | 0.59 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4304368 | 0.95 | TBXAS1 (0.76) | TBXAS1CYP2A6RECQLHRH1CHRNA7 | |
| SCHEMBL10772829 | 0.93 | TBXAS1 (0.77) | TBXAS1CYP2A6RECQLHRH1CHRNA7 | |
| SCHEMBL18248629 | 0.93 | TBXAS1 (0.77) | TBXAS1CYP2A6RECQLHRH1CHRNA7 | |
| SCHEMBL14959999 | 0.93 | TBXAS1 (0.77) | TBXAS1CYP2A6RECQLHRH1CHRNA7 | |
| SCHEMBL83186 | 0.91 | RECQL (0.62) | TBXAS1CYP2A6RECQLHRH1CHRNA7 | |
| Hydrochloric Acid SCHEMBL5349530 | 0.89 | TBXAS1 (0.61) | TBXAS1CYP2A6RECQLHRH1CHRNA7 | |
| SCHEMBL7165228 | 0.86 | TBXAS1 (0.68) | TBXAS1CYP2A6HRH1CHRNA7TDP1 | |
| SCHEMBL1583762 | 0.86 | TBXAS1 (0.90) | TBXAS1CYP2A6HRH1CHRNA7TDP1 | |
| SCHEMBL30612524 | 0.86 | TBXAS1 (0.90) | TBXAS1CYP2A6HRH1CHRNA7TDP1 | |
| SCHEMBL18248608 | 0.85 | TBXAS1 (0.65) | TBXAS1CYP2A6RECQLHRH1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103687860-B | As P2X7Heterocyclic amide derivatives of receptor antagonists | 埃科特莱茵药品有限公司 | 2016-06-08 | — | — | CN | claimed |
| CN-103687860-A | As P2X7Heterocyclic amide derivatives of receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2014-03-26 | — | — | CN | claimed |
| CN-102389425-A | Application of nicotinic acid derivates in preparation of medicaments for promoting follicular development and maintaining ovarian functions | CHINESE PLA GENERAL HOSPITAL | 2012-03-28 | — | — | CN | claimed |
| EP-0853618-B1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL -AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2011-08-17 | — | — | EP | claimed |
| CN-1812786-A | Use of pyrazolopyridines for the treatment of cognitive deficits | EXONHIT THERAPEUTICS SA (FR) | 2006-08-02 | — | — | CN | claimed |
| CN-1780821-A | Heterocyclic kinase inhibitors. | ABBOTT LAB (US) | 2006-05-31 | — | — | CN | claimed |
| CN-104837832-B | GDF-8 inhibitors | 里格尔药品股份有限公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-106536507-A | 2,3-disubstituted pyridine compounds as TGF-beta inhibitors and methods of use | 里格尔药品股份有限公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-103687860-B | As P2X7Heterocyclic amide derivatives of receptor antagonists | 埃科特莱茵药品有限公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-104837832-A | GDF-8 inhibitors | RIGEL PHARMACEUTICALS INC | 2015-08-12 | — | — | CN | disclosed |
| CN-102389425-B | Application of nicotinic acid derivates in preparation of medicaments for promoting follicular development and maintaining ovarian functions | CHINESE PLA GENERAL HOSPITAL | 2013-07-10 | — | — | CN | disclosed |
| EP-2454243-A2 | TETRAZOLE DERIVATIVES | Merck Serono SA (CH) | 2012-05-23 | — | — | EP | disclosed |
| CN-102389425-A | Application of nicotinic acid derivates in preparation of medicaments for promoting follicular development and maintaining ovarian functions | CHINESE PLA GENERAL HOSPITAL | 2012-03-28 | — | — | CN | disclosed |
| US-4131738-A | 6-Hydroxy-PGE1 compounds | THE UPJOHN COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4128713-A | 6,7-Didehydro-PGI1 compounds | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |
| US-4126744-A | PROSTACYCLIN, MUSCLE STIMULANTS, PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-4112224-A | PROSTAGLANDIN | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4109082-A | PROSTACYCLIN ANALOGS; SMOOTH MUSCLE STIMULATORS | THE UPJOHN COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4100192-A | Inter-phenylene-PG amides | THE UPJOHN COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4097489-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-06-27 | — | — | US | disclosed |