Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 2/20 | 0.34 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15047212 | 0.80 | NQO1 (0.58) | NQO1HRH3TTRCTSKALDH1A1 | |
| SCHEMBL17442633 | 0.80 | NQO1 (0.54) | NQO1SCN9ATTRSOS2CTSK | |
| SCHEMBL16881222 | 0.76 | NQO1 (0.54) | NQO1HRH3TTRSOS2CTSK | |
| SCHEMBL17442652 | 0.76 | NQO1 (0.54) | NQO1HRH3TTRSOS2CTSK | |
| SCHEMBL9176689 | 0.75 | HTR2A (0.53) | HRH3HTR2AHTR2CHTR2BTTR | |
| SCHEMBL25401591 | 0.75 | NQO1 (0.49) | NQO1ALDH1A1KDM4ETSHR | |
| SCHEMBL4301102 | 0.73 | MGAM (0.46) | SCN9AALDH1A1KDM4E | |
| SCHEMBL1688377 | 0.73 | NQO1 (0.58) | NQO1SCN9ATTRSOS2CTSK | |
| SCHEMBL6843917 | 0.73 | HTR2A (0.52) | HTR2AHTR2CHTR2BTTRALDH1A1 | |
| SCHEMBL21639257 | 0.71 | CTSS (0.57) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024272-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | Renovis, Inc. (US) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007133637-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | RENOVIS, INC. (US) | 2007-11-22 | — | — | WO | disclosed |