Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2454085 | 0.97 | PPARG (0.56) | PPARGPPARAHDAC3HDAC1HDAC2 | |
| SCHEMBL7290141 | 0.94 | KDM4E (0.51) | PPARGPPARAHDAC3HDAC1HDAC2 | |
| SCHEMBL1750042 | 0.90 | PTPN11 (0.57) | PPARGPPARAKDM4ETHRATHRB | |
| SCHEMBL10848345 | 0.89 | KDM4E (0.47) | PPARGPPARAHDAC3HDAC1HDAC2 | |
| SCHEMBL6043905 | 0.89 | KDM4E (0.47) | HDAC3HDAC1HDAC2KDM4EPOLB | |
| SCHEMBL1750021 | 0.89 | PPARG (0.61) | PPARGPPARAHDAC3HDAC1HDAC2 | |
| SCHEMBL11474981 | 0.88 | PPARG (0.50) | PPARGPPARAHDAC3HDAC1HDAC2 | |
| SCHEMBL11769955 | 0.87 | SMN1; SMN2 (0.55) | KDM4EPOLBAKR1C3AKR1C2SMN1; SMN2 | |
| SCHEMBL1546492 | 0.87 | KDM4E (0.57) | KDM4EPOLBAKR1C3AKR1C2SMN1; SMN2 | |
| SCHEMBL2448097 | 0.86 | PTPN11 (0.61) | KDM4EPOLBCYSLTR2CYSLTR1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112375168-B | Side chain rod-shaped polar liquid crystal polymer, preparation method thereof and application thereof in nonlinear optical field | 华南理工大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-112375168-A | Side chain rod-shaped polar liquid crystal polymer, preparation method thereof and application thereof in nonlinear optical field | 华南理工大学 | 2021-02-19 | — | — | CN | disclosed |
| CN-112342032-A | Rod-like polar liquid crystal molecule, preparation method thereof and rod-like polar nematic liquid crystal | 华南理工大学 | 2021-02-09 | — | — | CN | disclosed |
| US-20090069430-A1 | DIBENZENE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROPHARMA, S.A. (ES) | 2009-03-12 | — | — | US | disclosed |
| US-20090069430-A1 | DIBENZENE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROPHARMA, S.A. (ES) | 2009-03-12 | — | — | US | disclosed |
| US-20090069430-A1 | DIBENZENE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROPHARMA, S.A. (ES) | 2009-03-12 | — | — | US | disclosed |
| EP-1976823-A1 | DIBENZENE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | Neuropharma, S.A. (ES) | 2008-10-08 | — | — | EP | disclosed |
| EP-1014962-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2007068754-A1 | DIBENZENE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROPHARMA, S.A. (ES) | 2007-06-21 | — | — | WO | disclosed |
| EP-1019045-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2005-06-08 | — | — | EP | disclosed |
| US-20020173518-A1 | Antithrombotic agents | BEIGHT DOUGLAS WADE (US) | 2002-11-21 | — | — | US | disclosed |
| US-20020120007-A1 | Benzamide inhibitors of factor Xa | BEIGHT DOUGLAS WADE (US) | 2002-08-29 | — | — | US | disclosed |
| EP-1019045-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-03 | — | — | EP | disclosed |
| US-6372759-B1 | BLOOD COAGULATION FACTOR XA FOR MAMMALS | ELI LILLY AND COMPANY | 2002-04-16 | — | — | US | disclosed |
| US-6313122-B1 | AS INHIBITORS OF FACTOR XA AND ARE USED AS ANTICOAGULANTS IN MAMMALS | ELI LILLY AND COMPANY | 2001-11-06 | — | — | US | disclosed |
| EP-1019045-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| EP-1014962-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999000128-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |
| WO-1999000121-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069430-A1 | DIBENZENE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | CACNA1B, CACNB1, CACNA1C | PPARG 2459/4885PPARA 2017/4885HDAC3 4294/4885 |
| US-20020173518-A1 | Antithrombotic agents | SERPINC1, TFPI, F11 | PPARG 3664/4885PPARA 3821/4885HDAC3 624/4885 |
| US-20020120007-A1 | Benzamide inhibitors of factor Xa | TFPI, F11, F12 | PPARG 2764/4885PPARA 3286/4885HDAC3 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.