Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834433 | 0.95 | ALDH1A1 (0.40) | ALDH1A1HCAR3ABCB1ABCC1PKM | |
| SCHEMBL4300489 | 0.90 | ALDH1A1 (0.41) | ALDH1A1HCAR3ABCB1ABCC1PKM | |
| SCHEMBL6833502 | 0.87 | ALDH1A1 (0.38) | ALDH1A1HCAR3ABCB1ABCC1PKM | |
| SCHEMBL4308070 | 0.85 | ALDH1A1 (0.46) | ALDH1A1PKMLMNASMN1; SMN2MAPT | |
| SCHEMBL4306318 | 0.85 | ALDH1A1 (0.44) | ALDH1A1HCAR3ARPELP1LMNA | |
| SCHEMBL4303842 | 0.81 | ALDH1A1 (0.62) | ALDH1A1ABCB1LMNASMN1; SMN2MAPT | |
| SCHEMBL10779684 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HCAR3ABCB1ABCC1PKM | |
| SCHEMBL6834126 | 0.80 | TDP1 (0.45) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL7592119 | 0.80 | ALDH1A1 (0.35) | ALDH1A1HCAR3ABCB1ABCC1KDM4E | |
| SCHEMBL26530223 | 0.80 | MAPK1 (0.50) | ALDH1A1HCAR3LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598019-B2 | Method for cleavage of labile functional groups from chemical compounds | UNIVERSITAT KONSTANZ (DE) | 2009-10-06 | — | — | US | disclosed |
| US-7598019-B2 | Method for cleavage of labile functional groups from chemical compounds | UNIVERSITAT KONSTANZ (DE) | 2009-10-06 | — | — | US | disclosed |
| US-7598019-B2 | Method for cleavage of labile functional groups from chemical compounds | UNIVERSITAT KONSTANZ (DE) | 2009-10-06 | — | — | US | disclosed |
| US-20050255403-A1 | Method for cleavage of labile functional groups from chemical compounds | UNIVERSITAT KONSTANZ (DE) | 2005-11-17 | — | — | US | disclosed |
| US-20050170281-A1 | Method of cleaving labile functional groups from chemical compounds | NIMBLEGEN SYSTEMS, INC. | 2005-08-04 | — | — | US | disclosed |
| EP-1519941-A2 | A METHOD OF CLEAVING LABILE FUNCTIONAL GROUPS FROM CHEMICAL COMPOUNDS | Chemogenix GmbH (DE) | 2005-04-06 | — | — | EP | disclosed |
| WO-2004001033-A2 | A METHOD OF CLEAVING LABILE FUNCTIONAL GROUPS FROM CHEMICAL COMPOUNDS | CHEMOGENIX GMBH (DE) | 2003-12-31 | — | — | WO | disclosed |