Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4305092 | 0.90 | ALDH1A1 (0.44) | ALDH1A1ABCB1ABCC1KDM4EHCAR3 | |
| SCHEMBL6834433 | 0.84 | ALDH1A1 (0.40) | ALDH1A1ABCB1ABCC1KDM4EHCAR3 | |
| SCHEMBL16016739 | 0.81 | PDK1 (0.44) | ALDH1A1KDM4EHCAR3PDK1PKM | |
| SCHEMBL12782425 | 0.81 | ALDH1A1 (0.48) | ALDH1A1ABCB1ABCC1KDM4EHCAR3 | |
| SCHEMBL4303842 | 0.81 | ALDH1A1 (0.62) | ALDH1A1ABCB1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL395221 | 0.80 | ALDH1A1 (0.64) | ALDH1A1ABCB1ABCC1KDM4EPDK1 | |
| SCHEMBL30558592 | 0.80 | ALDH1A1 (0.64) | ALDH1A1ABCB1ABCC1KDM4EPDK1 | |
| SCHEMBL6234820 | 0.79 | PDK1 (0.41) | ALDH1A1ABCB1ABCC1KDM4EPDK1 | |
| SCHEMBL6833502 | 0.77 | ALDH1A1 (0.38) | ALDH1A1ABCB1ABCC1KDM4EHCAR3 | |
| SCHEMBL4308070 | 0.77 | ALDH1A1 (0.46) | ALDH1A1PKMMAPK1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598019-B2 | Method for cleavage of labile functional groups from chemical compounds | UNIVERSITAT KONSTANZ (DE) | 2009-10-06 | — | — | US | disclosed |
| US-7598019-B2 | Method for cleavage of labile functional groups from chemical compounds | UNIVERSITAT KONSTANZ (DE) | 2009-10-06 | — | — | US | disclosed |
| US-7598019-B2 | Method for cleavage of labile functional groups from chemical compounds | UNIVERSITAT KONSTANZ (DE) | 2009-10-06 | — | — | US | disclosed |
| US-20050255403-A1 | Method for cleavage of labile functional groups from chemical compounds | UNIVERSITAT KONSTANZ (DE) | 2005-11-17 | — | — | US | disclosed |
| EP-1480927-A2 | A METHOD FOR CLEAVAGE OF LABILE FUNCTIONAL GROUPS FROM CHEMICAL COMPOUNDS | Universität Konstanz (DE) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074542-A2 | A METHOD FOR CLEAVAGE OF LABILE FUNCTIONAL GROUPS FROM CHEMICAL COMPOUNDS | Universität Konstanz (DE) | 2003-09-12 | — | — | WO | disclosed |