Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | GRM8 | O00222 | 1/20 | 0.71 |
| ▸ | GRM6 | O15303 | 1/20 | 0.71 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.71 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.71 |
| ▸ | GSR | P00390 | 1/20 | 0.71 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.71 |
| ▸ | GRM5 | P41594 | 1/20 | 0.71 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.71 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.71 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.71 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.71 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.71 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.71 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.71 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.71 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.71 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.71 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.71 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25384088 | 1.00 | CYP1A2 (0.71) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL2538510 | 0.91 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL2538504 | 0.91 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL5369653 | 0.89 | GRIK1 (0.58) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL2750069 | 0.89 | CYP1A2 (0.58) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL5009811 | 0.87 | GSR (0.75) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL27182543 | 0.87 | GSR (0.56) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL29446324 | 0.87 | GSR (0.75) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL4298190 | 0.87 | GSR (0.75) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL16569602 | 0.86 | GRM8 (0.95) | CYP1A2GRM8GRM6GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090297494-A1 | Diagnostic and treatment of a mental disorder | CUENOD MICHEL | 2009-12-03 | — | — | US | claimed |
| EP-1709201-A1 | DIAGNOSTIC AND TREATMENT OF A MENTAL DISORDER | NOVARTIS FORSCHUNGSSTIFTUNG (CH) | 2006-10-11 | — | — | EP | claimed |
| WO-2005068649-A1 | DIAGNOSTIC AND TREATMENT OF A MENTAL DISORDER | NOVARTIS FORSCHUNGSSTIFTUNG (CH) | 2005-07-28 | — | — | WO | claimed |
| US-20130280381-A1 | YEAST, YEAST EXTRACT CONTAINING GAMMA-GLU-ABU, AND A METHOD FOR PRODUCING THE SAME | AJINOMOTO CO., INC. (JP) | 2013-10-24 | — | — | US | disclosed |
| US-20090297494-A1 | Diagnostic and treatment of a mental disorder | CUENOD MICHEL | 2009-12-03 | — | — | US | disclosed |
| EP-1709201-A1 | DIAGNOSTIC AND TREATMENT OF A MENTAL DISORDER | NOVARTIS FORSCHUNGSSTIFTUNG (CH) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005068649-A1 | DIAGNOSTIC AND TREATMENT OF A MENTAL DISORDER | NOVARTIS FORSCHUNGSSTIFTUNG (CH) | 2005-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090297494-A1 | Diagnostic and treatment of a mental disorder | GSTA1, GSR, GSTM1 | CYP1A2 4289/4885GRM8 129/4885GRM6 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.