Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13323322 | 0.81 | HTR6 (0.80) | HTR6MEN1KMT2ABCHE | |
| SCHEMBL3684432 | 0.76 | HTR6 (0.58) | HTR6HTR1ADRD2HTR2A | |
| SCHEMBL30285388 | 0.76 | HTR6 (0.58) | HTR6HTR1ADRD2HTR2A | |
| SCHEMBL3623511 | 0.75 | HTR6 (0.83) | HTR6HTR1ADRD2 | |
| SCHEMBL6568508 | 0.74 | HTR6 (0.57) | HTR6MEN1KMT2ABCHE | |
| SCHEMBL4845719 | 0.74 | MEN1 (0.53) | HTR6MEN1KMT2ABCHE | |
| SCHEMBL4312739 | 0.74 | HTR6 (0.56) | HTR6MEN1KMT2ABCHEDRD2 | |
| SCHEMBL31092832 | 0.74 | HTR6 (0.58) | HTR6ALOX5HTR1ADRD2HTR2A | |
| SCHEMBL3199486 | 0.74 | HTR6 (0.53) | HTR6MEN1KMT2ABCHE | |
| SCHEMBL4560894 | 0.73 | HTR6 (0.56) | HTR6MEN1KMT2ABCHEHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524839-B2 | Compounds, their use and preparation | BIOVITRUM AM (PUBL.) | 2009-04-28 | — | — | US | claimed |
| US-7087750-B2 | Compounds, their use and preparation | BIOVITRUM AB (SE) | 2006-08-08 | — | — | US | claimed |