Fluoride Ion

Fluoride Ion

SCHEMBL4307159

N#[N+]c1ccc(Br)cc1.[B+3].[F-].[F-].[F-].[F-]

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.44
ALDH1A1 P00352 4/20 0.35
ALOX15 P16050 2/20 0.35
MAPK1 P28482 2/20 0.35
CYP1A1 P04798 1/20 0.33
CYP1B1 Q16678 1/20 0.33
SLC22A2 O15244 1/20 0.32
SLC22A1 O15245 1/20 0.32
SLC22A3 O75751 1/20 0.32
PLAU P00749 1/20 0.32
GLB1 P16278 1/20 0.32
CTRB1 P17538 1/20 0.32
CTRC Q99895 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NOS1 P29475 2/20 0.31
FAAH O00519 1/20 0.31
MGLL Q99685 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112852 0.94
Water SCHEMBL809328 0.92 CYP2A6 (0.47) CYP2A6ALDH1A1ALOX15MAPK1CYP1A1
Hydrochloric Acid SCHEMBL3245514 0.92 CYP2A6 (0.47) CYP2A6ALDH1A1ALOX15MAPK1CYP1A1
SCHEMBL236958 0.84 CYP2A6 (0.40) CYP2A6ALDH1A1ALOX15MAPK1
SCHEMBL27830326 0.82 CYP2A6 (0.38) CYP2A6ALDH1A1ALOX15MAPK1
SCHEMBL809429 0.80 CYP2A6 (0.36) CYP2A6CA1CA2TSHR
SCHEMBL3238117 0.80 CYP2A6 (0.36) CYP2A6FAAHMGLLCA1CA2
Hydrochloric Acid SCHEMBL9017439 0.79 RAPGEF4 (0.38) CYP2A6ALDH1A1ALOX15MAPK1CYP1A1
SCHEMBL1304591 0.78
Hydrochloric Acid SCHEMBL11205797 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106928091-B Fluorochemical and its synthetic method 南开大学 2018-12-04 CN disclosed
WO-2009039181-A2 SULFONAMIDE-BASED ORGANOCATALYSTS AND METHOD FOR THEIR USE STATE OF OREGON ACTING BY & THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OR. STATE UNIV. (US) 2009-03-26 WO disclosed