SCHEMBL4307186

SCHEMBL4307186

c1ccc(C2COCN2)cc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
PRCP P42785 1/20 0.42
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
NPC1 O15118 1/20 0.38
SLC6A2 P23975 1/20 0.36
ADRA1A P35348 1/20 0.36
HTR2B P41595 1/20 0.36
SLC6A3 Q01959 1/20 0.36
SLC18A3 Q16572 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
GBA1 P04062 1/20 0.34
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C19 P33261 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14197992 1.00 TSHR (0.43) TSHRPRCPMEN1KMT2ANPC1
SCHEMBL13301525 1.00 TSHR (0.43) TSHRPRCPMEN1KMT2ANPC1
SCHEMBL1333525 0.79 PRKACA (0.49) TSHRPRCPMEN1KMT2ASLC6A2
SCHEMBL22097636 0.79 KDM1A (0.36) TSHRPRCPSLC6A2HTR2BSLC6A3
SCHEMBL30370485 0.79 KDM1A (0.36) TSHRPRCPSLC6A2HTR2BSLC6A3
SCHEMBL1333528 0.79 PRKACA (0.49) TSHRPRCPMEN1KMT2ASLC6A2
SCHEMBL1335278 0.79 PRKACA (0.49) TSHRPRCPMEN1KMT2ASLC6A2
SCHEMBL14197971 0.79 PRCP (0.40) TSHRPRCPMEN1KMT2ANPC1
SCHEMBL30370147 0.79 MAPT (0.47) PRCPMEN1KMT2AHTR2BKDM4E
Hydrochloric Acid SCHEMBL1849039 0.78 PRKACA (0.48) TSHRPRCPMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117601477-B Production process of colorful high-brightness hot-stamped reflective cloth Yeshili New Material Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-117601477-A Production process of colorful high-brightness hot-stamped reflective cloth 夜视丽新材料股份有限公司 2024-02-27 CN claimed
US-20170218007-A1 A PROCESS FOR THE PREPARATION OF NUCLEOSIDE PHOSPHORAMIDATE LUPIN LIMITED (IN) 2017-08-03 US claimed
EP-3174888-A1 A PROCESS FOR THE PREPARATION OF NUCLEOSIDE PHOSPHORAMIDATE Lupin Limited (IN) 2017-06-07 EP claimed
WO-2016016865-A1 A PROCESS FOR THE PREPARATION OF NUCLEOSIDE PHOSPHORAMIDATE LUPIN LIMITED (IN) 2016-02-04 WO claimed
CN-102504514-B Polyurethane self-molding material applicable to sports ground and application method thereof GUANGZHOU BATSMAN CHEMICAL CO LTD 2013-08-07 CN claimed
CN-102504514-A Polyurethane self-molding material applicable to sports ground and application method thereof GUANGZHOU BATSMAN CHEMICAL CO LTD 2012-06-20 CN claimed
CN-117601477-B Production process of colorful high-brightness hot-stamped reflective cloth Yeshili New Material Co.,Ltd. (CN) 2026-05-26 CN disclosed
WO-2025224179-A1 GLUTAMINYL CYCLASE INHBITORS FOR USE IN THE TREATMENT OF KIDNEY DISEASE VIVORYON THERAPEUTICS N.V. (DE) 2025-10-30 WO disclosed
CN-115927409-B Halohydrin dehalogenase mutant with improved stereoselectivity and activity and application thereof 合肥学院 2024-06-11 CN disclosed
CN-117693505-A Heteroaryl derivative compounds and uses thereof 沃若诺伊公司 2024-03-12 CN disclosed
CN-117601477-A Production process of colorful high-brightness hot-stamped reflective cloth 夜视丽新材料股份有限公司 2024-02-27 CN disclosed
WO-2024008166-A1 α,β-UNSATURATED AMIDE COMPOUND, AND PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 中国科学院上海药物研究所 2024-01-11 WO disclosed
CN-1566101-A Process for producing optically active hemiesters SUMITOMO CHEMICAL CO (JP) 2005-01-19 CN disclosed
CN-1163492-C 'Delta' 12,13-iso-taxol analogs, antineoplastic use and pharmaceutical compositions containing them �������Ŷ���Լ��������˾ 2004-08-25 CN disclosed
CN-1316414-A Process for preparing optically active half-esters SMITOMO CHEMICAL CO LTD (JP) 2001-10-10 CN disclosed
CN-1216039-A Process for preparing taxol UPJOHN CO (US) 1999-05-05 CN disclosed
US-5856473-A Process for preparing 1-(4-fluorophenyl)-3(R)-(3(S)-hydroxy-3-( phenyl or 4-fluorophenyl!)-propyl)-4(S)-(4-hydroxyphenyl)-2-azetidinone SCHERING CORPORATION (US) 1999-01-05 US disclosed
WO-1997016424-A1 PROCESS FOR PREPARING 1-(4-FLUOROPHENYL)-3(R)-(3(S)-HYDROXY-3-([PHENYL OR 4-FLUOROPHENYL])-PROPYL)-4(S)-(4-HYDROXYPHENYL)-2-AZETIDINONE SCHERING CORPORATION (US) 1997-05-09 WO disclosed
CN-1095377-A 7-halo-and 7 beta, 8 beta-methylene-paclitaxel, antitumor use and pharmaceutical composition containing the same UPJOHN CO (US) 1994-11-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170218007-A1 A PROCESS FOR THE PREPARATION OF NUCLEOSIDE PHOSPHORAMIDATE SAMHD1, PNP, MTAP TSHR 4226/4885PRCP 476/4885MEN1 4174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.