SCHEMBL4307281

SCHEMBL4307281

Fc1ccc(N(c2ccc(F)cc2F)c2ccc(F)cc2F)c(F)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
CA3 P07451 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
DDB1 Q16531 1/20 0.39
CRBN Q96SW2 1/20 0.39
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NFE2L2 Q16236 3/20 0.37
IDO1 P14902 2/20 0.37
AGXT P21549 2/20 0.37
HTT P42858 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2434424 0.86 ALDH1A1 (0.44) ALDH1A1CES2CES1CA3CA6
SCHEMBL5261755 0.82 DDB1 (0.42) ALDH1A1CES2CES1CA3CA6
SCHEMBL5531618 0.79 ALDH1A1 (0.42) ALDH1A1CES2CES1CA3CA6
SCHEMBL5716211 0.79 DDB1 (0.44) ALDH1A1CES2CES1CA3CA6
SCHEMBL13338139 0.79 DDB1 (0.44) ALDH1A1CES2CES1CA3CA6
SCHEMBL21279547 0.79 ALDH1A1 (0.42) ALDH1A1CES2CES1CA3CA6
SCHEMBL20671377 0.79 ACHE (0.44) ALDH1A1DDB1CRBNNFE2L2TSHR
SCHEMBL31327835 0.79 DPP4 (0.36) ALDH1A1CES2CES1CA3CA6
SCHEMBL14469220 0.77 DDB1 (0.42) ALDH1A1CES2CES1CA3CA6
Hydrochloric Acid SCHEMBL31098507 0.77 DDB1 (0.42) ALDH1A1CES2CES1CA3CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7585590-B2 Rechargeable lithium-ion cell with triphenylamine redox shuttle 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-09-08 US disclosed
EP-1994600-A2 RECHARGEABLE LITHIUM-ION CELL WITH TRIPHENYLAMINE REDOX SHUTTLE 3M Innovative Properties Company (US) 2008-11-26 EP disclosed
WO-2007097912-A2 RECHARGEABLE LITHIUM-ION CELL WITH TRIPHENYLAMINE REDOX SHUTTLE 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-08-30 WO disclosed
US-20070196727-A1 Rechargeable Lithium-Ion Cell with Triphenylamine Redox Shuttle 3M INNOVATIVE PROPERTIES COMPANY 2007-08-23 US disclosed