Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 5/20 | 0.38 |
| ▸ | CNR1 | P21554 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4308049 | 1.00 | CREBBP (0.46) | CREBBPEP300ALDH1A1HTTENPP2 | |
| SCHEMBL4309088 | 0.89 | CREBBP (0.43) | CREBBPEP300ALDH1A1HTTCYP3A4 | |
| SCHEMBL4310575 | 0.84 | CREBBP (0.53) | CREBBPEP300ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL4313076 | 0.82 | CREBBP (0.49) | CREBBPEP300ALDH1A1HTTCYP3A4 | |
| SCHEMBL4311026 | 0.79 | CREBBP (0.47) | CREBBPEP300ALDH1A1CYP3A4CNR2 | |
| SCHEMBL4315290 | 0.79 | CREBBP (0.58) | CREBBPEP300ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL10235987 | 0.78 | ALDH1A1 (0.49) | CREBBPEP300ALDH1A1GAANPSR1 | |
| SCHEMBL2526406 | 0.78 | CREBBP (0.48) | CREBBPEP300ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL3640912 | 0.78 | ALDH1A1 (0.46) | CREBBPEP300ALDH1A1HTTGAA | |
| SCHEMBL4305918 | 0.78 | CNR1 (0.45) | ALDH1A1ENPP2CYP3A4CYP2C9CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |