Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MDH1 | P40925 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4309070 | 1.00 | CNR1 (0.45) | CNR1ALDH1A1ENPP2DGAT2KDM4E | |
| SCHEMBL21998679 | 0.89 | KDM4E (0.55) | CNR1ALDH1A1ENPP2DGAT2KDM4E | |
| SCHEMBL21998921 | 0.89 | KDM4E (0.55) | CNR1ALDH1A1ENPP2DGAT2KDM4E | |
| SCHEMBL21998903 | 0.89 | KDM4E (0.55) | CNR1ALDH1A1ENPP2DGAT2KDM4E | |
| SCHEMBL4315477 | 0.89 | KDM4E (0.51) | CNR1ALDH1A1ENPP2DGAT2KDM4E | |
| SCHEMBL4310606 | 0.87 | HDAC3 (0.55) | CNR1ALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL4315463 | 0.87 | HDAC3 (0.55) | CNR1ALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL13625698 | 0.86 | ENPP2 (0.54) | CNR1ENPP2DGAT2LMNANPC1 | |
| SCHEMBL4303811 | 0.85 | TRPV1 (0.43) | CNR1ALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL10602139 | 0.82 | CNR1 (0.64) | CNR1ALDH1A1KDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |