Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | DUSP1 | P28562 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2624628 | 0.79 | HPGD (0.72) | TP53LMNAMAPTHPGDPTGS2 | |
| SCHEMBL2624626 | 0.79 | MAPT (0.71) | TP53LMNAMAPTHPGDPTGS2 | |
| SCHEMBL5978453 | 0.79 | MEN1 (0.79) | TP53MAPTHPGDPTGS2MMP2 | |
| SCHEMBL4513646 | 0.78 | MAPT (0.56) | TP53LMNAMAPTPTGS2MEN1 | |
| SCHEMBL7378302 | 0.74 | ALOX5 (0.80) | LMNAMAPTMEN1POLBKMT2A | |
| SCHEMBL21866227 | 0.72 | LCLAT1 (0.76) | LMNAMAPTHPGDMEN1POLB | |
| SCHEMBL4526536 | 0.72 | LMNA (0.79) | TP53LMNAMAPTHPGDPTGS2 | |
| SCHEMBL18585675 | 0.70 | MEN1 (0.68) | MAPTMMP13MEN1POLBKMT2A | |
| SCHEMBL8710919 | 0.70 | MEN1 (0.80) | LMNAMAPTMEN1POLBKMT2A | |
| SCHEMBL3145506 | 0.70 | TP53 (0.61) | TP53LMNAMAPTHPGDPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009113795-A2 | VECTOR AND METHOD FOR EXPRESSING AVIAN INFLUENZA VIRUS NEURAMINIDASE N1 IN E. COLI, METHOD OF USING THE VECTOR, AND NEURAMINIDASE INHIBITORS | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2009-09-17 | — | — | WO | claimed |
| WO-2009113795-A2 | VECTOR AND METHOD FOR EXPRESSING AVIAN INFLUENZA VIRUS NEURAMINIDASE N1 IN E. COLI, METHOD OF USING THE VECTOR, AND NEURAMINIDASE INHIBITORS | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2009-09-17 | — | — | WO | disclosed |