SCHEMBL4308357

SCHEMBL4308357

O=C(Oc1cc(Cl)c(Cl)cc1Cl)Oc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
FABP7 O15540 1/20 0.45
FABP3 P05413 1/20 0.45
FABP5 Q01469 1/20 0.45
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CUL4A Q13619 2/20 0.40
FKBP1A P62942 1/20 0.39
MAPK1 P28482 2/20 0.38
NR1I2 O75469 1/20 0.36
ADRA2A P08913 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
TACR2 P21452 1/20 0.36
DRD1 P21728 1/20 0.36
SLC6A2 P23975 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10751222 0.87 LMNA (0.55) LMNAFABP7FABP3FABP5TSHR
SCHEMBL432360 0.85 LMNA (0.47) LMNAFABP7FABP3FABP5TSHR
SCHEMBL30459416 0.85 LMNA (0.47) LMNAFABP7FABP3FABP5TSHR
SCHEMBL7105783 0.83 FABP7 (0.47) LMNAFABP7FABP3FABP5TSHR
SCHEMBL29781399 0.83 LMNA (0.46) LMNAFABP7FABP3FABP5TSHR
SCHEMBL10403921 0.83 LMNA (0.46) LMNAFABP7FABP3FABP5TSHR
SCHEMBL227733 0.83 LMNA (0.46) LMNAFABP7FABP3FABP5TSHR
SCHEMBL8898256 0.82 NPC1 (0.55) LMNAFABP7FABP3FABP5TSHR
SCHEMBL1984953 0.82 ELANE (0.43) LMNAFABP7FABP3FABP5TSHR
SCHEMBL30739992 0.82 ELANE (0.43) LMNAFABP7FABP3FABP5TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1896520-A2 POLYMERIZATION PROCESS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2008-03-12 EP claimed
US-20070043185-A1 Polymerization process E. I. DU PONT DE NEMOURS AND COMPANY 2007-02-22 US claimed
WO-2006133369-A2 POLYMERIZATION PROCESS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-12-14 WO claimed
EP-1551900-A1 POLYCARBONATE COPOLYMERS AND METHODS FOR PRODUCING THE POLYCARBONATE COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2005-07-13 EP claimed
EP-1519977-A1 POLYESTERCARBONATES AND METHODS OF MANUFACTURE GENERAL ELECTRIC COMPANY (US) 2005-04-06 EP claimed
WO-2004033529-A1 POLYCARBONATE COPOLYMERS AND METHODS FOR PRODUCING THE POLYCARBONATE COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2004-04-22 WO claimed
US-6689862-B2 MELT TRANSESTERIFICATION GENERAL ELECTRIC COMPANY 2004-02-10 US claimed
US-6689863-B1 Polycarbonate copolymers and methods for producing the polycarbonate copolymers GENERAL ELECTRIC COMPANY 2004-02-10 US claimed
WO-2004005368-A1 POLYESTERCARBONATES AND METHODS OF MANUFACTURE GENERAL ELECTRIC COMPANY (US) 2004-01-15 WO claimed
US-20040010112-A1 Polycarbonateester copolymer;impact strength, radiation transparent, heat resistance, waterproofing SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2004-01-15 US claimed
US-5250655-A Ester interchange catalyst; non-phosgene method MITSUBISHI PETROCHEMICAL COMPANY, LTD. (JP) 1993-10-05 US claimed
EP-0534189-A1 Method for producing polycarbonate MITSUBISHI CHEMICAL CORPORATION (JP) 1993-03-31 EP claimed
CN-107921103-A It is related to the method and composition of long half-lift coagulation complexes 细胞机械股份有限公司 2018-04-17 CN disclosed
EP-1558555-B1 METHOD FOR PURIFYING 1,1-BIS(4 -HYDROXY-3 -METHYLPHENYL )CYCLOHEXANE AND METHODS OF PRODUCING POLYCARBONATES THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2013-05-08 EP disclosed
US-7473752-B2 Functionalized silicone resins, methods for their preparation, and use as catalysts SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-01-06 US disclosed
EP-1896520-A2 POLYMERIZATION PROCESS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2008-03-12 EP disclosed
WO-2000026276-A2 METHOD OF MANUFACTURING POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2000-05-11 WO disclosed
EP-0902014-A1 PROCESS FOR PRODUCING ARYL CARBAMATES UBE INDUSTRIES LIMITED (JP) 1999-03-17 EP disclosed
US-3936452-A Process of producing pyrimidyl thiocarbonates NITTO BOSEKI CO., LTD. (JA) 1976-02-03 US disclosed
US-3932375-A PROTECTING GROUPS NITTO BOSEKI CO. LTD. (JA) 1976-01-13 US disclosed