SCHEMBL227733

SCHEMBL227733

O=C(Cl)Oc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
FABP7 O15540 1/20 0.44
FABP3 P05413 1/20 0.44
FABP5 Q01469 1/20 0.44
TSHR P16473 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
FKBP1A P62942 1/20 0.38
MAPK1 P28482 2/20 0.37
NR1I2 O75469 1/20 0.35
ADRA2A P08913 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
TACR2 P21452 1/20 0.35
DRD1 P21728 1/20 0.35
SLC6A2 P23975 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
ADORA1 P30542 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29781399 1.00 LMNA (0.46) LMNAFABP7FABP3FABP5TSHR
SCHEMBL4308357 0.83 LMNA (0.47) LMNAFABP7FABP3FABP5TSHR
SCHEMBL30459416 0.83 LMNA (0.47) LMNAFABP7FABP3FABP5TSHR
SCHEMBL432360 0.83 LMNA (0.47) LMNAFABP7FABP3FABP5TSHR
SCHEMBL7105783 0.81 FABP7 (0.47) LMNAFABP7FABP3FABP5TSHR
SCHEMBL10403921 0.81 LMNA (0.46) LMNAFABP7FABP3FABP5TSHR
SCHEMBL1701383 0.79 KDM4E (0.50) LMNAFABP7FABP3FABP5TSHR
SCHEMBL11216470 0.79 LMNA (0.44) LMNAFABP7FABP3FABP5TSHR
SCHEMBL29897301 0.79 KDM4E (0.50) LMNAFABP7FABP3FABP5TSHR
SCHEMBL21328032 0.77 KDM4E (0.49) LMNAFABP7FABP3FABP5TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 451 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4635941-A1 PROCESS FOR PREPARING A PEROXYESTER OR PEROXYCARBONATE Nouryon Chemicals International B.V. (NL) 2025-10-22 EP claimed
EP-4471010-B1 PROCESS FOR PREPARING A PEROXYESTER OR PEROXYCARBONATE NOURYON CHEMICALS INT BV (NL) 2025-06-04 EP claimed
US-20240400490-A1 PROCESS FOR PREPARING A PEROXYESTER OR PEROXYCARBONATE NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2024-12-05 US claimed
EP-4471010-A1 PROCESS FOR PREPARING A PEROXYESTER OR PEROXYCARBONATE Nouryon Chemicals International B.V. (NL) 2024-12-04 EP claimed
JP-2662311-B2 1997-10-08 JP claimed
EP-0553195-B1 BIOCOMPATIBLE MICROCAPSULES UNIV TEXAS (US) 1997-06-11 EP claimed
EP-0437563-B1 BIOLOGICALLY ACTIVE DRUG POLYMER DERIVATIVES DEBIO RECH PHARMA SA (CH) 1995-02-22 EP claimed
US-5286637-A Biologically active drug polymer derivatives and method for preparing same DEBIOPHARM, S.A. (CH) 1994-02-15 US claimed
EP-0290313-B1 PROCESS FOR OBTAINING ACTIVATED NITROSOCARBAMATES SANOFI (FR) 1992-03-04 EP claimed
EP-0437563-A1 BIOLOGICALLY ACTIVE DRUG POLYMER DERIVATIVES. DEBIOPHARM SA (CH) 1991-07-24 EP claimed
WO-1991001758-A1 BIOLOGICALLY ACTIVE DRUG POLYMER DERIVATIVES DEBIOPHARM S.A. (CH) 1991-02-21 WO claimed
US-4883903-A FROM CHLOROETHYLAMINE, A HALOFORMATE; AND NITROSYL SULFURIC ACID SANOFI (FR) 1989-11-28 US claimed
EP-4635941-A1 PROCESS FOR PREPARING A PEROXYESTER OR PEROXYCARBONATE Nouryon Chemicals International B.V. (NL) 2025-10-22 EP disclosed
US-20240400490-A1 PROCESS FOR PREPARING A PEROXYESTER OR PEROXYCARBONATE NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2024-12-05 US disclosed
EP-4471010-A1 PROCESS FOR PREPARING A PEROXYESTER OR PEROXYCARBONATE Nouryon Chemicals International B.V. (NL) 2024-12-04 EP disclosed
US-12016904-B2 Treatment of gastrointestinal bleeding in patients with severe von Willebrand disease by administration of recombinant VWF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-06-25 US disclosed
US-4883903-A FROM CHLOROETHYLAMINE, A HALOFORMATE; AND NITROSYL SULFURIC ACID SANOFI (FR) 1989-11-28 US disclosed
US-4376731-A 2-NITRILES THEREOF BOEHRINGER MANNHEIM GMBH (DE) 1983-03-15 US disclosed
US-4355172-A Process for 4-(D-3-amino-3-carboxypropoxy)-phenylglyoxylic acid oxime derivatives ELI LILLY AND COMPANY (US) 1982-10-19 US disclosed
US-3991205-A Inhibiting growth of bacteria and fungi with t-butyl 2,4,5-trichlorophenyl carbonate STAUFFER CHEMICAL COMPANY (US) 1976-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400490-A1 PROCESS FOR PREPARING A PEROXYESTER OR PEROXYCARBONATE GPX4, PRDX4, PRDX2 LMNA 1453/4885FABP7 1564/4885FABP3 1238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.