Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4303965 | 0.81 | XIAP (0.46) | ALDH1A1RAB9AMAPK1NPC1MEN1 | |
| SCHEMBL5591319 | 0.81 | CXCL8 (0.47) | MEN1POLBKMT2ALMNA | |
| SCHEMBL9031190 | 0.74 | ALDH1A1 (0.49) | ALDH1A1RAB9AMAPK1NPC1MEN1 | |
| SCHEMBL4306974 | 0.74 | ALDH1A1 (0.44) | ALDH1A1RAB9AMAPK1NPC1MEN1 | |
| SCHEMBL381318 | 0.72 | MEN1 (0.55) | ALDH1A1RAB9ANPC1MEN1MAPT | |
| SCHEMBL11557567 | 0.71 | EPHX1 (0.59) | ALDH1A1RAB9ANPC1MEN1POLB | |
| SCHEMBL11537710 | 0.71 | ALDH1A1 (0.41) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL2094466 | 0.71 | ALDH1A1 (0.51) | ALDH1A1RAB9AMAPK1NPC1MEN1 | |
| SCHEMBL2094463 | 0.71 | ALDH1A1 (0.47) | ALDH1A1RAB9AMAPK1NPC1MEN1 | |
| SCHEMBL9837096 | 0.71 | ALDH1A1 (0.47) | ALDH1A1RAB9AMAPK1NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127726-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-10-22 | — | — | WO | disclosed |
| WO-2009127726-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-10-22 | — | — | WO | disclosed |