Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010668 | 0.89 | PPARG (0.63) | PPARGAGTR1 | |
| SCHEMBL4012974 | 0.85 | PPARG (0.48) | PPARGCYP19A1EDNRAAGTR1CNR1 | |
| SCHEMBL4013891 | 0.76 | PPARG (0.61) | PPARGAGTR1 | |
| SCHEMBL4011358 | 0.76 | PPARG (0.61) | PPARGAGTR1 | |
| SCHEMBL9844285 | 0.75 | AGTR1 (0.46) | PPARGCYP19A1AGTR1 | |
| SCHEMBL7177667 | 0.74 | AGTR1 (0.63) | AGTR1 | |
| SCHEMBL4016245 | 0.74 | PPARG (0.47) | PPARGEDNRAAGTR1 | |
| SCHEMBL4009875 | 0.74 | PPARG (0.59) | PPARGAGTR1 | |
| SCHEMBL4313411 | 0.74 | PPARG (0.59) | PPARGAGTR1 | |
| SCHEMBL4012581 | 0.74 | PPARG (0.59) | PPARGAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |