Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4849644 | 0.71 | TDP1 (0.57) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11101556 | 0.70 | GRIN2D (0.51) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11101559 | 0.70 | GRIN2D (0.51) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8220455 | 0.69 | MAPT (0.50) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10041862 | 0.69 | MAPT (0.50) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24530076 | 0.67 | MAPT (0.68) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8709511 | 0.67 | MAPT (0.68) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11199924 | 0.67 | TDP1 (0.46) | MAPTTASP1ALDH1A1TDP1KMT2A | |
| SCHEMBL11199920 | 0.67 | TDP1 (0.46) | MAPTTASP1ALDH1A1TDP1KMT2A | |
| SCHEMBL3914151 | 0.66 | IDO1 (0.51) | MAPTCYP1A2CYP2C19L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127726-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-10-22 | — | — | WO | disclosed |