Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3925390 | 0.87 | ERCC5 (0.42) | IDO1HTTEPHX1ALDH1A1TDP1 | |
| SCHEMBL5096118 | 0.83 | KDM4E (0.50) | IDO1HTTEPHX1ALDH1A1KDM4E | |
| SCHEMBL3926026 | 0.83 | ALDH1A1 (0.39) | IDO1HTTALDH1A1MAPK1MAPT | |
| SCHEMBL5037814 | 0.82 | IDO1 (0.46) | IDO1HTTEPHX1ALDH1A1POLB | |
| SCHEMBL4302721 | 0.76 | L3MBTL1 (0.52) | IDO1HTTEPHX1POLBTDP1 | |
| SCHEMBL29718886 | 0.76 | L3MBTL1 (0.55) | IDO1HTTEPHX1ALDH1A1TDP1 | |
| SCHEMBL260323 | 0.76 | L3MBTL1 (0.55) | IDO1HTTEPHX1ALDH1A1TDP1 | |
| SCHEMBL895205 | 0.75 | IDO1 (0.54) | IDO1HTTTDP1CYP1A2CYP3A4 | |
| SCHEMBL29439097 | 0.75 | IDO1 (0.54) | IDO1HTTTDP1CYP1A2CYP3A4 | |
| SCHEMBL30274481 | 0.74 | TBXA2R (0.44) | IDO1HTTALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035374-A1 | N- (L-ALKYL-2- PHENYLETHYL) -CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES | Syngeta Participations AG (CH) | 2009-03-18 | — | — | EP | disclosed |
| EP-1992617-A1 | Optically active ethyl amides | Syngeta Participations AG (CH) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007141009-A1 | N- (L-ALKYL-2- PHENYLETHYL) -CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-12-13 | — | — | WO | disclosed |