Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | SLC33A1 | O00400 | 4/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4016028 | 0.92 | AGTR1 (0.52) | AGTR1PPARGSLC33A1PLA2G2A | |
| SCHEMBL4309196 | 0.76 | PPARG (0.40) | AGTR1PPARGSLC33A1PLA2G2A | |
| SCHEMBL4310825 | 0.71 | AGTR1 (0.53) | AGTR1PPARG | |
| SCHEMBL4010280 | 0.69 | PPARG (0.52) | AGTR1PPARGSLC33A1 | |
| SCHEMBL1888375 | 0.69 | AGTR1 (0.62) | AGTR1PPARG | |
| SCHEMBL4017109 | 0.69 | AGTR1 (0.46) | AGTR1PPARGSLC33A1 | |
| SCHEMBL4016033 | 0.66 | AGTR1 (0.49) | AGTR1PPARGSLC33A1LTB4R2 | |
| SCHEMBL27411498 | 0.65 | LTB4R2 (0.44) | AGTR1PPARGSLC33A1LTB4R2 | |
| SCHEMBL13277715 | 0.64 | AGTR1 (0.63) | AGTR1PPARG | |
| SCHEMBL4010324 | 0.64 | PPARG (0.44) | AGTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |