Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | STAMBP | O95630 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4303178 | 0.91 | KDM4E (0.41) | KDM4ECASP3MEN1KMT2AEGLN1 | |
| SCHEMBL17137748 | 0.87 | NR1H2 (0.37) | KDM4ECASP3MEN1KMT2AGAA | |
| SCHEMBL17137482 | 0.78 | KDM4E (0.39) | KDM4ECASP3MEN1KMT2AEGLN1 | |
| SCHEMBL4309932 | 0.75 | L3MBTL1 (0.38) | KDM4ECASP3GAARAB9AEGFR | |
| SCHEMBL4304768 | 0.72 | EGLN1 (0.46) | KDM4EEGLN1NPC1RAB9AALDH1A1 | |
| SCHEMBL4304567 | 0.70 | EGLN1 (0.60) | KDM4EMEN1KMT2AEGLN1GAA | |
| SCHEMBL17092707 | 0.68 | MAPT (0.45) | KDM4EGAANPC1RAB9AMAPT | |
| SCHEMBL4303176 | 0.67 | L3MBTL1 (0.38) | KDM4ECASP3MEN1KMT2AGAA | |
| SCHEMBL20593183 | 0.67 | TBXA2R (0.37) | — | |
| SCHEMBL1600124 | 0.66 | ALDH1A1 (0.51) | MEN1KMT2AGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134754-A1 | BENZOIMIDAZOLE GLYCINAMIDES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-05 | — | — | WO | disclosed |