⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2985930 | 0.79 | — | — | |
| SCHEMBL1404275 | 0.77 | CHRM2 (0.46) | — | |
| SCHEMBL8146532 | 0.77 | ALDH1A1 (0.54) | — | |
| SCHEMBL1493206 | 0.75 | — | — | |
| SCHEMBL217417 | 0.74 | — | — | |
| SCHEMBL315507 | 0.74 | — | — | |
| SCHEMBL10885990 | 0.74 | — | — | |
| SCHEMBL9602719 | 0.74 | ALDH1A1 (0.56) | — | |
| SCHEMBL843370 | 0.72 | ALDH1A1 (0.53) | — | |
| SCHEMBL538112 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 865 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114933598-B | 6-Substituted harmine derivative, and preparation method and application thereof | 乐山职业技术学院 | 2024-07-12 | — | — | CN | claimed |
| WO-2024005526-A1 | NOVEL COMPOUND AS NADPH OXIDASE 2 INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 동국대학교 산학협력단 | 2024-01-04 | — | — | WO | claimed |
| EP-3021847-B1 | SPIROQUINOXALINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH | HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM GESUNDHEIT & UMWELT GMBH (DE) | 2023-06-07 | — | — | EP | claimed |
| CN-113549080-B | 1,2, 3-triazolopyrimidine compounds, preparation method and application thereof | 中国医学科学院放射医学研究所 | 2023-05-16 | — | — | CN | claimed |
| CN-115991864-A | Aliphatic polyester with reversible crosslinking characteristic, and preparation method and application thereof | 上海梓龄化工技术有限公司 | 2023-04-21 | — | — | CN | claimed |
| WO-2023034413-A2 | METHODS AND AGENTS FOR MODULATING THE IMMUNE RESPONSE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-03-09 | — | — | WO | claimed |
| CN-113200967-B | Indole benzoquinone compound, preparation method and application thereof | 中国人民解放军陆军军医大学 | 2022-05-24 | — | — | CN | claimed |
| US-RE48992-E1 | Spiroquinoxaline derivatives as inhibitors of non-apoptotic regulated cell-death | HELMHOLTZ ZENTRUM MÜNCHEN-DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) | 2022-03-29 | — | — | US | claimed |
| CN-113200967-A | Indole benzoquinone compound, preparation method and application thereof | 中国人民解放军陆军军医大学 | 2021-08-03 | — | — | CN | claimed |
| US-20210122721-A1 | BIS-PROPENAMIDE COMPOUNDS AND METHODS OF TREATING CANCER | KING ABDULAZIZ UNIVERSITY (SA) | 2021-04-29 | — | — | US | claimed |
| EP-0081955-A2 | Benzo-fused heterocyclic compounds | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-06-22 | — | — | EP | claimed |
| US-4353734-A | PRE- AND POSTEMERGENCE | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1982-10-12 | — | — | US | claimed |
| US-4312990-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-01-26 | — | — | US | claimed |
| US-4268676-A | ANTITUMOR AGENTS | UNIVERSITY PATENTS, INC. (US) | 1981-05-19 | — | — | US | claimed |
| US-4208325-A | Preparation of 1-oxapenicillins and 4-acyloxy azetidinone intermediates therefor | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 1980-06-17 | — | — | US | claimed |
| US-4112230-A | Δ2,3 -1,4 Morpholine-2-carboxylic acid derivatives as antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1978-09-05 | — | — | US | claimed |
| US-4018782-A | 1-OXAPENICILLINS, ANTIBIOTICS | QUEEN'S UNIVERSITY (CA) | 1977-04-19 | — | — | US | claimed |
| US-4014892-A | ANTHELMINTICS | AMERICAN CYANAMID COMPANY (US) | 1977-03-29 | — | — | US | claimed |
| US-3992366-A | FOR CROSSLINKING PHOTOGRAPHIC GELATINS | CIBA-GEIGY AG (CH) | 1976-11-16 | — | — | US | claimed |
| US-3940391-A | HERBICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-24 | — | — | US | claimed |