SCHEMBL315507

SCHEMBL315507

[O]Cc1ccco1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL467449 0.87
SCHEMBL6584208 0.80
SCHEMBL8146532 0.79 ALDH1A1 (0.54)
SCHEMBL1404275 0.79 CHRM2 (0.46)
SCHEMBL919385 0.78
SCHEMBL217417 0.77
SCHEMBL3989569 0.76
SCHEMBL922272 0.76 ALDH1A1 (0.56)
SCHEMBL11677596 0.76
SCHEMBL43100 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108440591-B Synthesis method of chiral dihydrosilane compound 浙江大学 2021-03-05 CN claimed
US-20190010159-A1 NOVEL KINASE INHIBITOR AGAINST WILD-TYPE AND MUTANT EGFR PRECEDO PHARMACEUTICALS CO., LTD (CN) 2019-01-10 US claimed
EP-3398950-A1 NOVEL KINASE INHIBITOR AGAINST WILD-TYPE EGFR AND MUTATED EGFR Precedo Pharmaceuticals Co., Ltd. (CN) 2018-11-07 EP claimed
CN-108440591-A A kind of synthetic method of chiral two silane compound 浙江大学 2018-08-24 CN claimed
US-9139567-B2 Arylpyrazole ethers as inhibitors of leukotriene A4 hydrolase BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2015-09-22 US claimed
US-9018209-B2 Compounds and methods for the treatment of viruses and cancer YALE UNIVERSITY (US) 2015-04-28 US claimed
EP-2097415-B1 8-ETHINYLXANTHINE DERIVATIVES AS SELECTIVE A2A RECEPTOR ANTAGONISTS UNIV BONN (DE) 2014-10-29 EP claimed
US-20140221373-A1 ARYLPYRAZOLE ETHERS AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2014-08-07 US claimed
EP-2734516-A1 ARYLPYRAZOLE ETHERS AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE Boehringer Ingelheim International GmbH (DE) 2014-05-28 EP claimed
WO-2013012844-A1 ARYLPYRAZOLE ETHERS AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-01-24 WO claimed
EP-0208431-A1 Fungicidal pyridazines ELI LILLY AND COMPANY (US) 1987-01-14 EP claimed
CN-86104837-A FUNGICIDAL PYRISAZINES 1986-12-31 CN claimed
EP-0192213-A1 Mixture of yellow disperse dyes CASSELLA Aktiengesellschaft (DE) 1986-08-27 EP claimed
EP-0165900-A2 Lactones, their preparation and their use as herbicides CIBA-GEIGY AG (CH) 1985-12-27 EP claimed
US-4314943-A ANTIHYPERTENSIVE AGENTS; VASODILATORS MEAD JOHNSON & COMPANY (US) 1982-02-09 US claimed
US-4172806-A Endblocked furfuryloxy organosilicon dielectric fluids and electrical devices containing same DOW CORNING CORPORATION (US) 1979-10-30 US claimed
US-4170584-A INCORPORATION OF A FURAN COMPOUND INTO A VINYL CHLORIDE POLYMER ARMSTRONG CORK COMPANY (US) 1979-10-09 US claimed
US-4012421-A Organotin miticidal and insecticidal compounds STAUFFER CHEMICAL COMPANY (US) 1977-03-15 US claimed
US-3959296-A CARDIOVASCULAR AGENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US claimed
US-3954776-A ANTIARRHYTHMICS, ANAESTHETICS, ANALGESICS, ANTISECRETORY AGENTS YOSHITOMI PHARMECEUTICAL INDUSTRIES, LTD. (JA) 1976-05-04 US claimed