Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 18/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4311907 | 0.92 | AVPR1B (0.52) | AVPR1BHRH1SLC6A15 | |
| SCHEMBL4310057 | 0.89 | AVPR1B (0.49) | AVPR1B | |
| SCHEMBL4302954 | 0.88 | AVPR1B (0.53) | AVPR1B | |
| SCHEMBL4318184 | 0.86 | AVPR1B (0.55) | AVPR1B | |
| SCHEMBL4311903 | 0.82 | AVPR1B (0.48) | AVPR1B | |
| SCHEMBL4318180 | 0.78 | AVPR1B (0.50) | AVPR1B | |
| SCHEMBL4302952 | 0.77 | AVPR1B (0.46) | AVPR1B | |
| SCHEMBL4305854 | 0.75 | AVPR1B (0.42) | AVPR1B | |
| SCHEMBL4302843 | 0.73 | AVPR1B (0.58) | AVPR1B | |
| SCHEMBL4311066 | 0.71 | AVPR1B (0.41) | AVPR1BHRH1SLC6A15PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009130231-A1 | PYRROLO [1, 2-A] PYRAZINE DERIVATIVES AS VASOPRESSIN VIB RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-10-29 | — | — | WO | disclosed |