⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6261921 | 0.87 | ALDH1A1 (0.32) | — | |
| SCHEMBL6698489 | 0.77 | TSHR (0.31) | — | |
| SCHEMBL8677557 | 0.75 | — | — | |
| SCHEMBL158638 | 0.73 | — | — | |
| SCHEMBL9280238 | 0.72 | ALDH1A1 (0.33) | — | |
| SCHEMBL448123 | 0.70 | — | — | |
| SCHEMBL3214845 | 0.70 | TSHR (0.35) | — | |
| SCHEMBL2227816 | 0.70 | — | — | |
| SCHEMBL6390819 | 0.69 | TSHR (0.38) | — | |
| SCHEMBL1247374 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088828-A1 | Electrically Charged Implantable Medical Device | NICAST LTD. (IL) | 2009-04-02 | — | — | US | disclosed |
| EP-1885282-A2 | ELECTRICALLY CHARGED IMPLANTABLE MEDICAL DEVICE | Nicast Ltd. (IL) | 2008-02-13 | — | — | EP | disclosed |
| US-20070031607-A1 | Method and apparatus for coating medical implants | NICAST LTD. (IL) | 2007-02-08 | — | — | US | disclosed |
| WO-2006123340-A2 | ELECTRICALLY CHARGED IMPLANTABLE MEDICAL DEVICE | NICAST LTD. (IL) | 2006-11-23 | — | — | WO | disclosed |
| EP-1670595-A2 | METHOD AND APPARATUS FOR COATING MEDICAL IMPLANTS | Nicast Ltd. (IL) | 2006-06-21 | — | — | EP | disclosed |
| EP-1578306-A2 | MEDICATED POLYMER-COATED STENT ASSEMBLY | Nicast Ltd. (IL) | 2005-09-28 | — | — | EP | disclosed |
| WO-2005032400-A2 | METHOD AND APPARATUS FOR COATING MEDICAL IMPLANTS | NICAST LTD. (IL) | 2005-04-14 | — | — | WO | disclosed |
| US-20040030377-A1 | Medicated polymer-coated stent assembly | NICAST LTD. (IL) | 2004-02-12 | — | — | US | disclosed |
| WO-2002049535-A2 | MEDICATED POLYMER-COATED STENT ASSEMBLY | NICAST LTD. (IL) | 2002-06-27 | — | — | WO | disclosed |