Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.59 |
| ▸ | CCR5 | P51681 | 1/20 | 0.59 |
| ▸ | CCR8 | P51685 | 1/20 | 0.59 |
| ▸ | ATP4A | P20648 | 1/20 | 0.49 |
| ▸ | ATP4B | P51164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1715320 | 0.98 | CCR1 (0.61) | CCR1CCR5CCR8ATP4AATP4B | |
| SCHEMBL4303286 | 0.96 | CCR1 (0.59) | CCR1CCR5CCR8ATP4AATP4B | |
| SCHEMBL2431810 | 0.96 | CCR1 (0.59) | CCR1CCR5CCR8ATP4AATP4B | |
| SCHEMBL4296866 | 0.96 | CCR1 (0.59) | CCR1CCR5CCR8ATP4AATP4B | |
| SCHEMBL30284810 | 0.96 | CCR1 (0.59) | CCR1CCR5CCR8ATP4AATP4B | |
| SCHEMBL28085917 | 0.96 | CCR1 (0.59) | CCR1CCR5CCR8ATP4AATP4B | |
| SCHEMBL862479 | 0.80 | CCR1 (0.68) | CCR1CCR5CCR8KDM4ETSHR | |
| SCHEMBL5669092 | 0.76 | KDM4E (0.46) | ATP4AATP4BHTTSLC6A2KDM4E | |
| SCHEMBL16132489 | 0.76 | CCR1 (0.61) | CCR1CCR5CCR8L3MBTL1CYP1A2 | |
| SCHEMBL136654 | 0.75 | CCR1 (1.00) | CCR1CCR5CCR8HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-20070018568-A1 | Organic electroluminescent device | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2007-01-25 | — | — | US | disclosed |
| US-20060228577-A1 | Organic electroluminescent device | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2006-10-12 | — | — | US | disclosed |
| US-20050275341-A1 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2005-12-15 | — | — | US | disclosed |
| EP-1599074-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Kabushiki Kaisha Toyota Jidoshokki (JP) | 2005-11-23 | — | — | EP | disclosed |
| EP-1560469-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Kabushiki Kaisha Toyota Jidoshokki (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050275341-A1 | Coumarin compound | XPO1, VKORC1, XPO5 | CCR1 355/4885CCR5 1452/4885CCR8 1315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.