SCHEMBL862479

SCHEMBL862479

Cc1cnc2c(C)cccc2c1C

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.68
CCR5 P51681 1/20 0.68
CCR8 P51685 1/20 0.68
PARP1 P09874 2/20 0.47
HTR1A P08908 1/20 0.46
ADRA1D P25100 1/20 0.46
ADRA1A P35348 1/20 0.46
ADRA1B P35368 1/20 0.46
NPC1 O15118 2/20 0.45
HSP90AA1 P07900 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CYP2A6 P11509 2/20 0.44
CYP1A2 P05177 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.40
KDM4E B2RXH2 1/20 0.39
TSHR P16473 1/20 0.39
ELANE P08246 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16132489 0.82 CCR1 (0.61) CCR1CCR5CCR8PARP1NPC1
SCHEMBL1715320 0.82 CCR1 (0.61) CCR1CCR5CCR8PARP1NPC1
SCHEMBL136654 0.81 CCR1 (1.00) CCR1CCR5CCR8NPC1HSP90AA1
SCHEMBL28297883 0.81 CCR1 (1.00) CCR1CCR5CCR8NPC1HSP90AA1
Zinc Ion SCHEMBL1714698 0.80 CCR1 (0.59) CCR1CCR5CCR8PARP1HTR1A
SCHEMBL1714865 0.80 CCR1 (0.59) CCR1CCR5CCR8PARP1HTR1A
SCHEMBL2431810 0.80 CCR1 (0.59) CCR1CCR5CCR8PARP1NPC1
SCHEMBL4310097 0.80 CCR1 (0.59) CCR1CCR5CCR8PARP1NPC1
SCHEMBL4303286 0.80 CCR1 (0.59) CCR1CCR5CCR8PARP1L3MBTL1
SCHEMBL4296866 0.80 CCR1 (0.59) CCR1CCR5CCR8PARP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180053868-A1 PHOTOELECTRIC CONVERSION DEVICE HAVING REFLECTION PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-22 US disclosed
US-20180053868-A1 PHOTOELECTRIC CONVERSION DEVICE HAVING REFLECTION PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-22 US disclosed
US-20170174703-A1 QUINOLINE DERIVATIVES AS SMO INHIBITORS GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) 2017-06-22 US disclosed
US-20170162808-A1 PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-08 US disclosed
US-20170162808-A1 PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-08 US disclosed
US-20160372675-A1 MACROMOLECULAR COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-22 US disclosed
US-9512149-B2 Reactive compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-06 US disclosed
US-9512149-B2 Reactive compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-06 US disclosed
US-9472763-B2 Macromolecular compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-10-18 US disclosed
US-9396831-B2 Polymer compound and electronic device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-19 US disclosed
US-20120205641-A1 PHOTOVOLTAIC CELL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-16 US disclosed
US-8142908-B2 Polymer light-emitting material comprising a conjugated polymer and compound exhibiting light emission from the triplet excited state and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-27 US disclosed
US-20120008068-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-12 US disclosed
US-8012603-B2 Polyanilines; strong fluorescence and large charge transporting properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-06 US disclosed
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-06-12 US disclosed
US-20080118773-A1 Complex Composition, Polymer Complex Compound And Polymer Light-Emitting Device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-05-22 US disclosed
US-20080003422-A1 Polymer Compound, Polymer Thin Film and Polymer Thin Film Device Using the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-01-03 US disclosed
US-20070103059-A1 Composition and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-10 US disclosed
US-20070051922-A1 Polymer light-emitting material and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-08 US disclosed
US-20070040164-A1 Polymer complex compound and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties BRS3, SLC43A1, MRPS23 CCR1 70/4885CCR5 521/4885CCR8 403/4885
US-20170174703-A1 QUINOLINE DERIVATIVES AS SMO INHIBITORS SMO, GLI1, SHH CCR1 4734/4885CCR5 3295/4885CCR8 4601/4885
US-20160372675-A1 MACROMOLECULAR COMPOUND EXOSC4, TRPC6, MRPS22 CCR1 288/4885CCR5 2067/4885CCR8 1548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.